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Brook Chemical Limited

31

Basic Information

Company Name:Brook Chemical Limited

Business Type:Chemical manufacturer

Total NO.Employees:

Country/Region:China

Certificates:

Year Established:

Introduction of Brook Chemical Limited

Web: www.chembrook.com TEL:+86 (21) 5276-2796 Fax:+86 (21) 5206-2290 Email:[email protected],[email protected]

Products of Brook Chemical Limited

  • Chemical Name: Amlodipine (maleate)
    CAS No.: 88150-47-4 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Quality Control & MSDS Files:
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  • Chemical Name: Desloratadine
    CAS No.: 100643-71-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Clarinex;Neoclarityn;Sch341... Quality Control & MSDS Files:
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    Brief introduction:

    Desloratadine(Sch34117) is a potent antagonist for human histamine H1 receptor used to treat allergies. Target: Histamine H1 Receptor Desloratadine binds to the human H1 receptor with Ki value of 0.87 nM in displacing tritiated mepyramine.

  • Chemical Name: Medetomidine (hydrochloride)
    CAS No.: 86347-15-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Domitor hydrochloride;MPV78... Quality Control & MSDS Files:
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    Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties. Target: Adrenergic alpha-2 Receptor Medetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ab...

  • Chemical Name: Nitrendipine
    CAS No.: 39562-70-4 Purity: Appearances: light yellow to green yellow Solid
    Brand: Synonyms: Ethyl methyl 1,4-dihydro-2,... Quality Control & MSDS Files:
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    Nitrendipine is a calcium channel blocker with marked vasodilator action. Target: Calcium Channel Nitrendipine is a dihydropyridine calcium channel blocker.

  • Chemical Name: Dexmedetomidine (hydrochloride)
    CAS No.: 145108-58-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((S)-alpha,2,3-Trimethylb... Quality Control & MSDS Files:
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    Dexmedetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties. Target: Adrenergic alpha-2 Receptor Dexmedetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, ...

  • Chemical Name: Amlodipine
    CAS No.: 88150-42-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Norvasc;Istin;Intervask; 3-... Quality Control & MSDS Files:
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    Amlodipine is a long-acting calcium channel blocker. Target: Calcium Channel Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells.

  • Chemical Name: Nimodipine
    CAS No.: 66085-59-4 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 1,4-Dihydro-2,6-dimethyl-4-... Quality Control & MSDS Files:
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    Nimodipine(Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy. Target: Calcium Channel Nimodipine is main use is in the prevention of cerebral vasospasm and resultant ischemia, a complica...

  • Chemical Name: Glipizide
    CAS No.: 29094-61-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Glucotrol;Minidiab;CP 28720... Quality Control & MSDS Files:
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    Glipizide is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes. Target: Potassiun Channel Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class.

  • Chemical Name: Dofetilide
    CAS No.: 115256-11-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N-[4-(2-{2-[4-(methanesulph... Quality Control & MSDS Files:
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    Dofetilide(Tikosyn) is a class III antiarrhythmic agent. Target: Potassium Channel In patients with congestive heart failure and reduced left ventricular function, dofetilide was effective in converting atrial fibrillation, preventing its recurrence, and reducing the risk of hospitalization for worsening heart failure.

  • Chemical Name: Detomidine (hydrochloride)
    CAS No.: 90038-01-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 5-(2,3-dimethylbenzyl)-1H-i... Quality Control & MSDS Files:
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    Detomidine hydrochloride produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist Target: α2-adrenergic agonist Detomidine is an imidazole derivative and α2-adrenergic agonist, used as a large animal sedative, primarily used in horses.

  • Chemical Name: Phenformin (hydrochloride)
    CAS No.: 834-28-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 1-Phenethylbiguanide hydroc... Quality Control & MSDS Files:
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    Phenformin, an anti-diabetic drug, has demonstrated antitumor activity both in vitro and in vivo. IC50 Value: Target: Anticancer in vitro: Treatment with phenformin significantly delayed the development of resistance to PLX4720 in cultured melanoma cells.

  • Chemical Name: Glimepiride
    CAS No.: 93479-97-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Amaryl;Glimperide; 3-ethyl-... Quality Control & MSDS Files:
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    Glimepiride(Amaryl) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg. Target: DPP4 Glimepiride (Hoe 490) is a new sulfonylurea.

  • Chemical Name: Cetirizine (dihydrochloride)
    CAS No.: 83881-52-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 2-(2-{4-[(4-Chlorophenyl)(p... Quality Control & MSDS Files:
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    Cetirizine 2Hcl, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.

  • Chemical Name: γ-Formylpyridine
    CAS No.: 872-85-5 Purity: Appearances: clear brown-yellow
    Brand: Synonyms: Isonicotinaldehyde; Pyridin... Quality Control & MSDS Files:
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  • Chemical Name: Lansoprazole
    CAS No.: 103577-45-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: AG-1749;AG1749;AG 1749; 2-(... Quality Control & MSDS Files:
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    Lansoprazole(AG 1749) is a proton pump inhibitor which prevents the stomach from producing acid. Target: Proton Pump Lansoprazole, a substituted benzimidizole proton pump inhibitor, on pharmacokinetics and metabolism of theophylline has been studied in healthy adults given oral lansoprazole 30 mg once daily for 11 days.

  • Chemical Name: Cilnidipine
    CAS No.: 132203-70-4 Purity: Appearances: light yellow to green yellow Solid
    Brand: Synonyms: (+/-)-(E)-Cinnamyl 2-methox... Quality Control & MSDS Files:
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    Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.

  • Chemical Name: Nisoldipine
    CAS No.: 63675-72-9 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 1,4-Dihydro-2,6-dimethyl-4-... Quality Control & MSDS Files:
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    Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.

  • Chemical Name: Tiotropium (Bromide)
    CAS No.: 136310-93-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (1a,2b,4b,5a,7b)-7-[(Hydrox... Quality Control & MSDS Files:
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    Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. IC50 value: Target: mAChR Tiotropium Bromide stops signaling between neurons and leads to muscle relaxation.

  • Chemical Name: Loratadine
    CAS No.: 79794-75-5 Purity: Appearances: White to off-white solid
    Brand: Synonyms: SCH 29851;Loratidine;SCH298... Quality Control & MSDS Files:
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    Loratadine(SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. IC50 value: 32 uM Target: H1-receptor Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.

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