• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

Biochem Tek(Shanghai) Co., ltd.

28

Basic Information

Company Name:Biochem Tek(Shanghai) Co., ltd.

Business Type:Chemical manufacturer

Total NO.Employees:

Country/Region:China

Certificates:

Year Established:

Introduction of Biochem Tek(Shanghai) Co., ltd.

Web: www.biochemtek.com TEL:+86 (21) 5199-1287 Fax: Email:[email protected]

Products of Biochem Tek(Shanghai) Co., ltd.

  • Chemical Name: Harpagoside
    CAS No.: 19210-12-9 Purity: Appearances:
    Brand: Synonyms: [(1S,4aS,5R,7S,7aS)-4a,5-Di... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

  • Chemical Name: (+)-Bicuculline
    CAS No.: 485-49-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (R-(R*,S*))-6-(5,6,7,8-Tetr... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

  • Chemical Name: Teniposide
    CAS No.: 29767-20-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Vumon;VM-26;VM26;VM 26; (5R... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Teniposide(VM-26) is a semisynthetic derivative of podophyllotoxin and are increasingly used in cancer medicine; causing breaks in DNA via an interaction with DNA topoisomerase II. IC50 value: Target: Topo II Teniposide is a phase-specific cytotoxic drug acting in the late S and early G2 phases of the cell cycle.

  • Chemical Name: Valspodar
    CAS No.: 121584-18-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Cyclo[[(2S,4R,6E)-4-methyl-... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Valspodar(PSC833) is a P-glycoprotein (P-gp) inhibitor widely used in preclinical and clinical studies for overcoming multidrug resistance (MDR).

  • Chemical Name: Varespladib
    CAS No.: 172732-68-2 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: [[3-(Aminooxoacetyl)-2-ethy... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    LY315920 (Varespladib) is a potent and selective human non-pancreatic secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM. IC50 value: 7 nM Target: sPLA2 in vitro: LY315920 exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50 of 8.1...

  • Chemical Name: LY404039
    CAS No.: 635318-11-5 Purity: Appearances: White to gray solid
    Brand: Synonyms: LY 404039;LY-404039; (1R,4S... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    LY404039 is an inhibitor for mGluR1(Ki=149 nM) and mGluR2(Ki= 92 nM), which can also inhibit dopamine receptor. IC50 Value:149 nM(Ki for mGlu2); 92 nM(Ki for mGlu3)[1] Target: mGluR1; mGluR2 Metabotropic glutamate (mGlu) receptors have been shown to mediate a number of behaviors including emotionality and responsivity to stress as d...

  • Chemical Name: Dalcetrapib
    CAS No.: 211513-37-0 Purity: Appearances: White to off-white solid
    Brand: Synonyms: JTT-705;RO-4607381;JTT705;J... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Dalcetrapib (JTT-705; RO-4607381) is a rhCETP inhibitor with IC50 of 0.2 μM that increases the plasma HDL cholesterol.

  • Chemical Name: Dapagliflozin
    CAS No.: 461432-26-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: BMS-512148;BMS512148;BMS 51... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Dapagliflozin(BMS512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) is in development for the treatment of type 2 diabetes mellitus (T2DM).

  • Chemical Name: Saquinavir (Mesylate)
    CAS No.: 149845-06-7 Purity: Appearances: White to off-white solid
    Brand: Synonyms: (S)-N1-((2S,3R)-4-((3S,4aS,... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Saquinavir mesylate is an HIV Protease Inhibitor used in antiretroviral therapy.

  • Chemical Name: Entinostat
    CAS No.: 209783-80-2 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: MS-275; SNDX-275; MS 275; S... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Entinostat (MS-275; SNDX 275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM. IC50 Value: 0.51 μM(HDAC1); 1.7 μM(HDAC3) Target: HDAC1/3 in vitro: MS-275 shows inhibitory to HDACs by 2'-amino group.

  • Chemical Name: XAV-939
    CAS No.: 284028-89-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: XAV939; NVP-XAV 939; 2-(4-(... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    XAV939 is a small molecule and selective Wnt pathway transcription factor β-catenin-mediated transcription inhibitor and axin stabilizing agent with IC50 of 11 and 4 nM for the inhibition of TNKS1 and TNKS2, respectively. IC50 Value: 11 nM(TNKS1); 4 nM(TNKS2) Target: TMKS1/2; β-catenin in vitro: XAV-939 specifically inhibits tankyr...

  • Chemical Name: Semagacestat
    CAS No.: 425386-60-3 Purity: Appearances: White to off-white solid
    Brand: Synonyms: LY450139;LY-450139;LY 45013... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM. IC50 value: 10.9/12.1/12.0 nM (Aβ42/Aβ40/Aβ38); 14.1 nM (Notch signaling) [1] in vitro: Semagacestat reduces the secretion of Aβ42, Aβ40 and Aβ38 from H4 human glioma ...

  • Chemical Name: Vismodegib
    CAS No.: 879085-55-9 Purity: Appearances: White to off-white solid
    Brand: Synonyms: GDC-0449;GDC 0449;GDC0449; ... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Vismodegib(GDC-0449) is a more potent novel and specific synthetic oral hedgehog pathway inhibitor with an IC50 of 3 nM; also inhibits P-gp with IC50 of 3.0 μM. IC50 value: 3 nM (hedgehog); 3.0 uM (P-gp) [1] Target: hedgehog in vitro: GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cel...

  • Chemical Name: GDC-0879
    CAS No.: 905281-76-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: GDC0879;GDC 0879; (E)-5-(1-... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    GDC-0879 is a novel, potent, and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well; no inhibition known to other protein kinases. IC50 value: 0.13 nM [1] Target: B-Raf in vitro: GDC-0879 also inhibits cellular pERK with IC50 of 63 nM.

  • Chemical Name: Abiraterone
    CAS No.: 154229-19-3 Purity: Appearances: White to off-white solid
    Brand: Synonyms: 17-(3-Pyridyl)androsta-5,16... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Abiraterone (CB-7598) is a potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM.

  • Chemical Name: TW-37
    CAS No.: 877877-35-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: TW 37;TW37; N-(4-((2-(tert-... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively. IC50 Value: 0.29 μM (Ki for Bcl-2) Target: Bcl-2 Family in vitro: TW-37 shows significant anti-proliferative and pro-apoptotic effect in a de novo chemo-resistant WSU-DLCL2 lymphoma cell line and primar...

  • Chemical Name: Vatalanib (dihydrochloride)
    CAS No.: 212141-51-0 Purity: Appearances: Off-white to pink Solid
    Brand: Synonyms: PTK787 dihydrochloride;PTK/... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Vatalanib (PTK787; ZK-222584; CGP-79787) is an inhibitor of <b>VEGFR2/KDR</b> with <b>IC<sub>50</sub></b> of 37 nM.

  • Chemical Name: BEZ235
    CAS No.: 915019-65-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: NVP-BEZ 235;BEZ-235;BEZ 235... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM/5 nM/7 nM/75 nM/6 nM, respectively; inhibits ATR with IC50 of 21 nM; shown to be poor inhibitory to Akt and PDK1. IC50 value: 4 nM/5 nM/7 nM/75 nM/6 nM(p110α/γ/δ/β/mTOR) [1] Target: PI3K/mTOR in vitro: BEZ235 sign...

  • Chemical Name: Motesanib
    CAS No.: 453562-69-1 Purity: Appearances: White to off-white solid
    Brand: Synonyms: AMG 706; AMG-706; N-(3,3-di... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. IC50 value: 2 nM/3 nM/6 nM/8 nM(VEGFR1/2/3/c-Kit) [1] Target: pan-VEGFR; Kit in vitro: Motesanib Diphosphate has broad activity agains...

<Previous 1 2 ... Next>