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Chemical Name:
GBR 12935
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CAS No.:
76778-22-8
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Synonyms: GBR12935;GBR-12935; 1-(2-(b... |
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Brief introduction:
GBR 12935 is a potent, and selective dopamine reuptake inhibitor.
IC50 value:
Target: dopamine reuptake inhibitor
in vitro: The calculated Kd of [3H]GBR-12935 binding to CYP2D6 was 42.2 nM, indicating that GBR-12935 has a high affinity for CYP2D6.
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Chemical Name:
Citarinostat
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CAS No.:
1316215-12-9
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Appearances: White to off-white Solid |
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Synonyms: ACY241;ACY-241;ACY 241 |
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Brief introduction:
Citarinostat (ACY-241) is an orally available selective <b>HDAC6</b> inhibitor with IC50 of 2.6 nM and 46 nM for HDAC6 and HDAC3, respectively. It has 13 to 18-fold selectivity towards HDAC6 in comparison to HDAC1-3.
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Chemical Name:
D-Mannitol 1,2:5,6-bis-acetonide
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CAS No.:
1707-77-3
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Appearances: White to off-white Solid |
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Synonyms: D-Mannitol diacetonide; 1,2... |
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Chemical Name:
Berbamine (dihydrochloride)
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CAS No.:
6078-17-7
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Appearances: White to off-white Solid |
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Brief introduction:
Berbamine dihydrochloride is an inhibitor of <b>NF-κB</b> activity with remarkable anti-myeloma efficacy.
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Chemical Name:
Garenoxacin
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CAS No.:
194804-75-6
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Synonyms: Ganefloxacin; Garenfloxacin... |
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Brief introduction:
Garenoxacin is a novel oral des-fluoro(6) quinolone with potent antimicrobial activity against common respiratory pathogens, including resistant strains. It has favourable pharmacokinetic profiles for maximum plasma concentration (Cmax) and area under the plasma concentration-time curve (AUC), with good penetration into sputum and otor...
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Chemical Name:
7-CHLORO-4-QUINAZOLINOL
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CAS No.:
31374-18-2
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Synonyms: 7-chloroquinazolin-4(3H)-one |
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Chemical Name:
Efaproxiral (sodium)
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CAS No.:
170787-99-2
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Appearances: White to off-white Solid |
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Synonyms: RSR13 sodium |
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Brief introduction:
Efaproxiral Sodium is a synthetic allosteric modifier of <b>hemoglobin</b>, used for brain metastases originating from breast cancer.
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Chemical Name:
4-Chloro-3-nitroquinoline
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CAS No.:
39061-97-7
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Synonyms: 3-Nitro-4-chloroquinoline; ... |
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Chemical Name:
SB 242084 (hydrochloride)
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CAS No.:
1049747-87-6
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Appearances: White to off-white Solid |
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Synonyms: SB-242084 hydrochloride |
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Brief introduction:
5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity.
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Chemical Name:
Quisinostat
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CAS No.:
875320-29-9
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Purity: |
Appearances: Light yellow to yellow Solid |
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Synonyms: JNJ-26481585 |
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Brief introduction:
Quisinostat (JNJ-26481585) is an orally available, potent <b>HDAC</b> inhibitor with <b>IC<sub>50</sub></b> values of 0.11 nM for HDAC1.
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Chemical Name:
thiazole-2-carboxylic acid
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CAS No.:
14190-59-1
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Synonyms: thiazole-2-carboxylic acid |
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Chemical Name:
Pyrimidin-2-yl-methylamine
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CAS No.:
75985-45-4
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Synonyms: pyrimidin-2-ylmethanamine |
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