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Beijing Lang Rebone Technology Co., Ltd.

14

Basic Information

Company Name:Beijing Lang Rebone Technology Co., Ltd.

Business Type:Chemical manufacturer since 2013

Total NO.Employees:

Country/Region:China

Certificates:

Year Established:

Introduction of Beijing Lang Rebone Technology Co., Ltd.

Web: www.langrb.com TEL:+86 (10) 5979-9429 / +86 18612220856 Fax:+86 (10) 8895-6459 Email:[email protected]

Products of Beijing Lang Rebone Technology Co., Ltd.

  • Chemical Name: Olopatadine (hydrochloride)
    CAS No.: 140462-76-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (Z)-11-[3-(Dimethylamino)pr... Quality Control & MSDS Files:
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    Brief introduction:

    Olopatadine HCl is a histamine blocker used to treat allergic conjunctivitis. Target: Histamine Receptor Olopatadine is one of the second-generation histamine H1 receptor antagonists that are treated for allergic disorders.

  • Chemical Name: Ivabradine (hydrochloride)
    CAS No.: 148849-67-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 3-[3-[[(8S)-3,4-Dimethoxy-8... Quality Control & MSDS Files:
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    Brief introduction:

    Ivabradine hydrochloride, a new If inhibitor with IC 50 of 2.9 μM, which is a pure heart rate lowering agent.

  • Chemical Name: Dabigatran etexilate (mesylate)
    CAS No.: 872728-81-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Pradaxa;BIBR 1048MS;Dabigat... Quality Control & MSDS Files:
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    Brief introduction:

    Dabigatran etexilate mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran.

  • Chemical Name: Cisatracurium (besylate)
    CAS No.: 96946-42-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Nimbex; (1R,1'R,2R,2'R)-2,2... Quality Control & MSDS Files:
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    Brief introduction:

    Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission. Target: AChR alpha-2 Cisatracurium is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctivel...

  • Chemical Name: Icotinib
    CAS No.: 610798-31-7 Purity: Appearances:
    Brand: Synonyms: BPI-2009; N-(3-ethynylpheny... Quality Control & MSDS Files:
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    Brief introduction:

    Icotinib(BPI-2009) is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R). IC50 value: 5 nM Target: EGFR and EGFR mutants in vitro: Icotinib inhibits EGFR activity in a dose-depende...

  • Chemical Name: Methotrexate
    CAS No.: 59-05-2 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: (+)-Amethopterin; (+)-4-Ami... Quality Control & MSDS Files:
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    Brief introduction:

    Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. IC50 Value: Target: antifolate in vitro: In normal T cells, Methotrexate (MTX) produced a dose-dependent reduction in de novo adenosine and guan...

  • Chemical Name: Asenapine (maleate)
    CAS No.: 85650-56-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Saphris maleate;Org 5222 ma... Quality Control & MSDS Files:
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    Brief introduction:

    Asenapine maleate(Org 5222 maleate) inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.

  • Chemical Name: Voglibose
    CAS No.: 83480-29-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 5-(1,3-Dihydroxypropan-2-yl... Quality Control & MSDS Files:
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    Brief introduction:

    Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia. Target: α-glucosidases glibose can inhibit the intestinal α-glucosidases, which are responsible for the digestion of disaccharides such as ma...

  • Chemical Name: Apixaban
    CAS No.: 503612-47-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: BMS-562247-01; BMS 562247-0... Quality Control & MSDS Files:
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    Brief introduction:

    Apixaban(BMS-562247-01) is a direct factor Xa inhibitor with an IC50 of 0.22±0.02 μM.

  • Chemical Name: Bepotastine (Beslilate)
    CAS No.: 190786-44-8 Purity: Appearances: White to yellow solid
    Brand: Synonyms: (+)-(S)-4-[4-[1-(4-Chloroph... Quality Control & MSDS Files:
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    Brief introduction:

    Bepotastine Beslilate (Bepreve) is a histamine H1 receptor anatagonist.

  • Chemical Name: Enzalutamide
    CAS No.: 915087-33-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: MDV3100;MDV-3100; MDV 3100;... Quality Control & MSDS Files:
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    Brief introduction:

    Enzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM. IC50 value: 36 nM [1] Target: androgen-receptor in vitro: Enzalutamide has greater affinity to AR than Bicalutamide does in a competition assay with 16β-[18F]fluoro-5α-DHT (18-FDHT) in castration-resistant LNCaP/AR cells (AR-overexpressing).

  • Chemical Name: Silodosin
    CAS No.: 160970-54-7 Purity: Appearances: White to off-white solid
    Brand: Synonyms: 1-(3-Hydroxypropyl)-5-[(2R)... Quality Control & MSDS Files:
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    Brief introduction:

    Silodosin (Rapaflo; KMD-3213) is an α1-adrenoceptor antagonist with high uroselectivity; In treatment of dysuria. IC50 Value: Target: Adrenergic Receptor in vitro: Silodosin potently inhibited 2-[2-(4-hydroxy-3-[125I]iodophenyl)ethylaminomethyl]-alpha-tetralone binding to the cloned human alpha 1a-AR, with a Ki value of 0.036 nM, bu...

  • Chemical Name: Regorafenib
    CAS No.: 755037-03-7 Purity: Appearances: White to off-white solid
    Brand: Synonyms: BAY 73-4506; BAY73-4506; 4-... Quality Control & MSDS Files:
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    Brief introduction:

    Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. IC50 value: Target: VEGFR; Raf; PDGFRβ in vitro: Regorafenib strongly prevents VEGFR2 autophosphorylation in NIH-3T3/VEGFR2 cells with IC50 of 3 nM.