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AvaChem Scientific LLC

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Basic Information

Company Name:AvaChem Scientific LLC

Business Type:Chemical manufacturer

Total NO.Employees:

Country/Region:USA

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Introduction of AvaChem Scientific LLC

Web: www.avachem.com TEL:+1 (210) 667-3815 Fax:+1 (210) 592-6206 Email:[email protected]

Products of AvaChem Scientific LLC

  • Chemical Name: Monoammonium glycyrrhizinate hydrate
    CAS No.: 53956-04-0 Purity: Appearances:
    Brand: Synonyms: Glycyrrhizin Monoammonium S... Quality Control & MSDS Files:
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    Brief introduction:

    Ammonium glycyrrhizate is a commercial flavorant and emulsifer found in Glycyrrhiza. It inhibits 11β-HSD and is used to treat herpes virus infection. It inhibits viral entry to host cells, prevents glial inflammation and kaninic acid-induced neuronal death, and suppresses DMH-induced carcinogenesis.

  • Chemical Name: Sinomenine
    CAS No.: 115-53-7 Purity: Appearances:
    Brand: Synonyms: Cucoline, Kukoline Quality Control & MSDS Files:
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    Brief introduction:

    Sinomenine is a blocker of the <b>NF-κB</b> activation and also an activator of <b>μ-opioid receptor</b>.

  • Chemical Name: Genistein
    CAS No.: 446-72-0 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 4',5,7-Trihydroxyisoflavone... Quality Control & MSDS Files:
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    Brief introduction:

    Genistein(NPI 031L), a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. IC50 Value: It has been shown that genistein inhibits many type of cancers including prostat...

  • Chemical Name: Apigenin
    CAS No.: 520-36-5 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 4',5,7-Trihydroxyflavone;Ap... Quality Control & MSDS Files:
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    Brief introduction:

    Apigenin is a competitive <b>CYP2C9</b> inhibitor with a <b>K<sub>i</sub></b> of 2 μM.

  • Chemical Name: Kaempferol
    CAS No.: 520-18-3 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 3,4',5,7-Tetrahydroxyflavon... Quality Control & MSDS Files:
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    Brief introduction:

    Kaempferol(Kempferol) is a relatively common nontoxic, natural dietary compound which has been reported to reduce the risk of ovarian cancer. IC50 value: Kaempferol inhibits proliferation of ovarian cancer cells at 40μM or higher concentrations[2]. Target: Anticancer Kaempferol (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-...

  • Chemical Name: Emodin
    CAS No.: 518-82-1 Purity: Appearances: Light yellow to yellow
    Brand: Synonyms: 1,3,8-Trihydroxy-6-methylan... Quality Control & MSDS Files:
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    Brief introduction:

    Emodin is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in cancer cells that are regulated by different signaling pathways. IC50 Value: observed at 72 hr were as follows: 66.9 uM, Hep3B cells; 74.36 uM, HepG2 cells; and 101.5 uM, Huh7 cells [1]. Target:NF-kB si...

  • Chemical Name: Bafetinib
    CAS No.: 859212-16-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: INNO-406;NS-187 Quality Control & MSDS Files:
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    Brief introduction:

    Bafetinib (INNO-406) is a potent and selective dual <b>Bcr-Abl/Lyn</b> inhibitor with <b>IC50</b> of 5.8 nM/19 nM in cell-free assays, does not inhibit the phosphorylation of the T315I mutant and is less potent to PDGFR and c-Kit. Phase 2.

  • Chemical Name: Paclitaxel
    CAS No.: 33069-62-4 Purity: Appearances: white-yellow solid
    Brand: Synonyms: Taxol; (2aR,4S,4aS,6R,9S,11... Quality Control & MSDS Files:
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    Brief introduction:

    Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. IC50 Value: 0.1 pM Target: microtubule in vitro: Paclitaxel inhibits non-endothelial type human cells at 104 - to 105 -fold higher concentrations, with IC50 of 1 nM-10 nM.

  • Chemical Name: Docetaxel
    CAS No.: 114977-28-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N-debenzoyl-N-tert-butoxyca... Quality Control & MSDS Files:
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    Docetaxel(Taxotere), an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules. IC50 Value: Target: Microtubule/Tubulin in vitro: IC50 concentrations (reducing survival by 50%) ranged from 0.13-3.3 ng/ml, with three neuroblastoma lines proving most sensitive and three breast a...

  • Chemical Name: Gemcitabine (Hydrochloride)
    CAS No.: 122111-03-9 Purity: Appearances: White to off-white solid
    Brand: Synonyms: 4-Amino-1-[3,3-difluoro-4-h... Quality Control & MSDS Files:
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    Brief introduction:

    GemcitabineHcl (LY 188011 Hcl) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. IC50 Value: 50 nM( PANC1); 40 nM(MIAPaCa2); 18 nM(BxPC3 ); 12 nM(Capan2) Target: Nucleoside antimetabolite/analog Gemcitabine is converted intracellularly to the active meta...

  • Chemical Name: Gemcitabine
    CAS No.: 95058-81-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: LY 188011;NSC 613327;Zefei;... Quality Control & MSDS Files:
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    Brief introduction:

    Gemcitabine(LY-188011; NSC 613327) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. IC50 Value: 50 nM( PANC1); 40 nM(MIAPaCa2); 18 nM(BxPC3 ); 12 nM(Capan2) Target: Nucleoside antimetabolite/analog Gemcitabine is converted intracellularly to the active ...

  • Chemical Name: Vinorelbine
    CAS No.: 71486-22-1 Purity: Appearances:
    Brand: Synonyms: Navelbine;Navelbine base;KW... Quality Control & MSDS Files:
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    Brief introduction:

    Vinorelbine(KW-2307 base) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM. IC50 value: Target: Anti-mitotic Vinorelbine (Navelbine) is the first 5′NOR semi-synthetic vinca alkaloid and exerts its activity through the MAPK (p38) pathway with median IC90 and IC50 of 15.5 and 2.3 μM.

  • Chemical Name: Bufalin
    CAS No.: 465-21-4 Purity: Appearances: White to off-white solidd
    Brand: Synonyms: 3-b,14-Dihydroxy-5-beta-buf... Quality Control & MSDS Files:
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    Brief introduction:

    Bufalin is an inhibitor of steroid receptor coactivator 3 (SRC-3). It acts by inducing cell death through the ROS-mediated RIP1/RIP3/PARP-1 pathways.

  • Chemical Name: 3-Hydroxy-4H-pyran-4-one
    CAS No.: 496-63-9 Purity: Appearances:
    Brand: Synonyms: 3-Hydroxypyran-4-one; NSC 7... Quality Control & MSDS Files:
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  • Chemical Name: Taurochenodeoxycholic acid
    CAS No.: 516-35-8 Purity: Appearances:
    Brand: Synonyms: 2-((R)-4-((3R,5S,7R,8R,9S,1... Quality Control & MSDS Files:
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    Brief introduction:

    Taurochenodeoxycholic acid is one of the main bioactive substances of animals' bile acid.

  • Chemical Name: Canadine
    CAS No.: 522-97-4 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 5,8,13,13a-Tetrahydro-9,10-... Quality Control & MSDS Files:
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  • Chemical Name: Rosmarinic acid
    CAS No.: 537-15-5 Purity: Appearances:
    Brand: Synonyms: 3-(3,4-Dihydroxyphenyl)-2-[... Quality Control & MSDS Files:
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  • Chemical Name: Palmatine
    CAS No.: 3486-67-7 Purity: Appearances:
    Brand: Synonyms: 2,3,9,10-Tetramethoxy-5,6-d... Quality Control & MSDS Files:
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    Brief introduction:

    Palmatine, an isoquinoline alkaloid, has sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities.

  • Chemical Name: Picrinine
    CAS No.: 4684-32-6 Purity: Appearances:
    Brand: Synonyms: (2R,6S,7aR,12aR,12bS,14R,E)... Quality Control & MSDS Files:
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