Ascent Scientific
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Basic Information
Company Name:Ascent Scientific
Business Type:Chemical manufacturer
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Products of Ascent Scientific
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Chemical Name:
Capsazepine
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CAS No.:
138977-28-3
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Purity: |
Appearances: White to off-white solid |
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Synonyms: N-(4-chlorophenethyl)-7,8-d... |
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Brief introduction:
Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, capsaicin; potent TRPV1 receptor antagonist with 562 nM.
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Chemical Name:
AM630
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CAS No.:
164178-33-0
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: [6-Iodo-2-methyl-1-[2-(4-mo... |
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Brief introduction:
AM630 is a selectivity CB2 antagonist with Ki of 31.2 nM; > 150 fold selectivity over CB1 receptor.
IC50 Value: 31.2 nM
Target: CB2 receptor
AM630 is a selective CB2 receptor antagonist that binds to CB1 and CB2 receptors with Ki values of 5.2 uM and 31.2 nM, respectively.
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Chemical Name:
SB 203580
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CAS No.:
152121-47-6
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Purity: |
Appearances: White to off-white solid |
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Synonyms: 4-(4-Fluorophenyl)-2-(4-met... |
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Brief introduction:
SB203580(RWJ 64809) is a p38 MAPK inhibitor with IC50 of 0.3-0.5 uM.
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Chemical Name:
SB 216763
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CAS No.:
280744-09-4
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Purity: |
Appearances: Pink to red solid |
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Synonyms: SB-216763;SB216763; 3-(2,4-... |
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Brief introduction:
SB 216763 is potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 9 nM); competes with ATP.
IC50 value: 9 nM (Ki)
Target: GSK-3α
SB 216763 has minimal activity against 24 other protein kinases (IC50 > 10 μ M).
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Chemical Name:
3-Methyl-7-chloro-1,2,4-benzothiadiazine 1,1-dioxide
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CAS No.:
364-98-7
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: Sch-6783;SRG-95213 |
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Brief introduction:
Diazoxide is an ATP-sensitive <b>potassium channel</b> activator ; can be used to treat hyperinsulinism.
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Chemical Name:
Ruthenium Red
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CAS No.:
11103-72-3
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Synonyms: C.I. 77800; Ruthenium oxych... |
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Brief introduction:
Blocks Ca2+ uptake and release from mitochondria, and Ca2+ release from ryanodine-sensitive intracellular stores. Also blocks cell membrane-located capsaicin-activated cation channels (IC50 = 14 nM) and voltage-sensitive Ca2+ channels to inhibit neurotransmitter release.
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Chemical Name:
Pirenzepine (dihydrochloride)
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CAS No.:
29868-97-1
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Synonyms: LS519 |
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Brief introduction:
Pirenzepine dihydrochloride (LS519) is a selective <b>M1</b> muscarinic receptor antagonist.
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Chemical Name:
JWH 015
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CAS No.:
155471-08-2
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Synonyms: JWH015; JWH 015; JWH-015. |
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Brief introduction:
Selective CB2 agonist (Ki values are 13.8 and 383 nM as measured at human cloned CB2 and CB1 receptors expressed in CHO cells).
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