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Ark Pharm, Inc.

594314

Basic Information

Company Name:Ark Pharm, Inc.

Business Type:Chemical manufacturer

Total NO.Employees:

Country/Region:USA

Certificates:

Year Established:

Introduction of Ark Pharm, Inc.

Web: www.arkpharminc.com TEL:+1 (847) 367-3680 Fax:+1 (847) 367-3681 Email:[email protected]

Products of Ark Pharm, Inc.

  • Chemical Name: AMG 837 calcium hydrate
    CAS No.: 1259389-38-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: AMG-837 calcium hydrate;AMG... Quality Control & MSDS Files:
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    Brief introduction:

    AMG 837 calcium hydrate is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. IC50 value: 13 nM (EC50) [1] Target: GPR40 agonist AMG 837 displayed the expected two-fold increase in potency on GPR4 (EC50 = 13 [±7] nM) compared to the rac...

  • Chemical Name: AMG 837 sodium salt
    CAS No.: 865231-45-4 Purity: Appearances:
    Brand: Synonyms: AMG-837 sodium salt;AMG837 ... Quality Control & MSDS Files:
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    Brief introduction:

    AMG 837 sodium salt is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. IC50 value: 13 nM (EC50) [1] Target: GPR40 agonist AMG 837 displayed the expected two-fold increase in potency on GPR4 (EC50 = 13 [±7] nM) compared to the racemic...

  • Chemical Name: PEAQX
    CAS No.: 459836-30-7 Purity: Appearances:
    Brand: Synonyms: NVP-AAM077 Quality Control & MSDS Files:
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    Brief introduction:

    NVP-AAM077 inhibited progenitor cells proliferation in the subventricular zone and dentate gyrus and reduced the survival of newborn cells in the dentate gyrus in the adult mice.

  • Chemical Name: LY2857785
    CAS No.: 1619903-54-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: LY 2857785;LY-2857785; (1r,... Quality Control & MSDS Files:
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    Brief introduction:

    LY2857785 is a type I reversible and competitive ATP kinase inhibitor against <b>CDK9</b> (<b>IC<sub>50</sub></b> 11 nM) and other transcription kinases <b>CDK8</b> (<b>IC<sub>50</sub></b> 16 nM), and <b>CDK7</b> (<b>IC<sub>50</sub></b> 246 nM).

  • Chemical Name: (R)-(+)-Etomoxir sodium salt
    CAS No.: 828934-41-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (+)-Etomoxir sodium salt; s... Quality Control & MSDS Files:
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    Brief introduction:

    (R)-(+)-Etomoxir (sodium salt) is a potent inhibitor of carnitine palmitoyltransferase I (CPT1); inhibits β-oxidation in mitochondria; shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells.

  • Chemical Name: IM-12
    CAS No.: 1129669-05-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: IM 12;IM12; 3-((4-fluorophe... Quality Control & MSDS Files:
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    Brief introduction:

    IM-12 is an inhibitor of <b>GSK-3β</b>, with an <b>IC<sub>50</sub></b> of 53 nM, and also enhances Wnt signalling.

  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
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    Brief introduction:

    Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM; no inhibition on other HDAC forms. IC50 value: 5 nM [1] Target: HDAC6 inhibitor Nexturastat A displayed low micromolar activity compared to the low nanomolar activity against HDAC6.

  • Chemical Name: kb-NB77-78
    CAS No.: 1350622-33-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 9-((tert-butyldimethylsilyl... Quality Control & MSDS Files:
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    Brief introduction:

    kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).

  • Chemical Name: MMAD hydrochloride
    CAS No.: 173441-26-4 Purity: Appearances: White to off-white solid
    Brand: Synonyms: Demethyldolastatin 10 hydro... Quality Control & MSDS Files:
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    A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).

  • Chemical Name: 3,4-Diethoxybenzonitrile
    CAS No.: 60758-87-4 Purity: Appearances:
    Brand: Synonyms: 3,4-diethoxybenzonitrile Quality Control & MSDS Files:
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  • Chemical Name: Boc-Phe-OH
    CAS No.: 13734-34-4 Purity: Appearances:
    Brand: Synonyms: BOC-L-Phenylalanine;N-(tert... Quality Control & MSDS Files:
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  • Chemical Name: HG6-64-1
    CAS No.: 1315329-43-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: HG-6-64-1;HG 6-64-1; (E)-N-... Quality Control & MSDS Files:
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    Brief introduction:

    HG6-64-1 is a potent and selective <b>B-Raf</b> inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a <b>IC<sub>50</sub></b> of 0.09 μM on B-raf V600E transformed Ba/F3 cells.

  • Chemical Name: 4SC-202 free base
    CAS No.: 910462-43-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4SC 202 free base;4SC202 fr... Quality Control & MSDS Files:
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    Brief introduction:

    4SC-202 free base is an orally available potent HDACi specific for class I HDAC isoenzymes(NO HDAC8) with IC50s of 1.2/1.12/0.57 uM for HDAC1/2/3; high selectivity over ClassIIa/IIb/III HDACs. IC50 value: Target: HDAC1/2/3 The novel HDACi 4SC-202 is an orally available potent HDACi specific for class I HDAC isoenzymes.

  • Chemical Name: Dictamnine
    CAS No.: 484-29-7 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 4-Methoxyfuro[2,3-b]quinoli... Quality Control & MSDS Files:
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    Brief introduction:

    Dictamnine (Dictamine) has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; A natural plant product has been reported to have antimicrobial activity against bacteria and fungi. IC50 value: Target: Dictamnine has antimicrobial activities against the model fungus Saccharomyces cerevisiae, with a min...

  • Chemical Name: Arg-Gly-Asp-Ser
    CAS No.: 91037-65-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: RGDS peptide;Fibronectin In... Quality Control & MSDS Files:
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    Brief introduction:

    Arg-Gly-Asp-Ser(RGDS peptide) is an integrin binding sequence that inhibits integrin receptor function; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9.

  • Chemical Name: Defactinib
    CAS No.: 1073154-85-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: VS-6063;VS6063;VS 6063; N-m... Quality Control & MSDS Files:
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    Brief introduction:

    Defactinib is a novel <b>FAK</b> inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.