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Apichem Chemical Technology Co., Ltd.

41

Basic Information

Company Name:Apichem Chemical Technology Co., Ltd.

Business Type:Chemical manufacturer

Total NO.Employees:

Country/Region:China

Certificates:

Year Established:

Introduction of Apichem Chemical Technology Co., Ltd.

Web: www.apichem.net TEL:+86 (21) 6199-2249 Fax:+86 (21) 5196-9751 Email:[email protected],[email protected]

Products of Apichem Chemical Technology Co., Ltd.

  • Chemical Name: Tirofiban
    CAS No.: 144494-65-5 Purity: Appearances:
    Brand: Synonyms: (2S)-2-(Butylsulfonylamino)... Quality Control & MSDS Files:
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    Brief introduction:

    Tirofiban(L700462;MK383) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist Target: integrin IIb/IIIa Tirofiban hydrochloride monohydrate blocks platelet aggregation and thrombus formation.

  • Chemical Name: Pantoprazole
    CAS No.: 102625-70-7 Purity: Appearances:
    Brand: Synonyms: Protonix;SKF96022; 6-(diflu... Quality Control & MSDS Files:
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    Pantoprazole(SKF96022; Protonix) is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. IC50 value: Target: proton pump inhibitor

  • Chemical Name: Pimobendan
    CAS No.: 74150-27-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Vetmedin;Acardi;pimobendane... Quality Control & MSDS Files:
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    Brief introduction:

    Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM. Target: PDE3 Pimobendan exhibits selective inhibition of PDE III isolated from guinea pig cardiac muscle with IC50 of 0.32 uM compared to the inhibition of PDE I and PDE II (IC50s >30 μM).

  • Chemical Name: Zonisamide (sodium)
    CAS No.: 68291-98-5 Purity: Appearances:
    Brand: Synonyms: AD 810 sodium;CI 912 sodium... Quality Control & MSDS Files:
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    Brief introduction:

    Zonisamide sodium is a 1,2 benzisoxazole derivative and the first agent of this chemical class to be developed as an antiepileptic drug. Target: Calcium channel inhibitor; Sodium channel inhibitor Zonisamide sodium is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures for adul...

  • Chemical Name: Dienogest
    CAS No.: 65928-58-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 2-((8S,13S,14S,17R)-17-hydr... Quality Control & MSDS Files:
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    Brief introduction:

    Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis.

  • Chemical Name: Amprenavir
    CAS No.: 161814-49-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: [(3S)-Oxolan-3-yl] N-[(2S,3... Quality Control & MSDS Files:
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    Brief introduction:

    Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection. IC50 Value: 0.6 nM (Ki); Against wild-type clinical HIV isolates:14.6 +/- 12.5 ng/mL (mean +/- SD) [1]. Target: HIV protease in vitro: Amprenavir has an enzyme inhibition constant (Ki = 0.6 nM) that falls within the Ki range of the other prote...

  • Chemical Name: Tesmilifene
    CAS No.: 98774-23-3 Purity: Appearances:
    Brand: Synonyms: DPPE; 2-(4-benzylphenoxy)-N... Quality Control & MSDS Files:
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  • Chemical Name: Pergolide
    CAS No.: 66104-22-1 Purity: Appearances:
    Brand: Synonyms: 8beta-[(Methylthio)methyl]-... Quality Control & MSDS Files:
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  • Chemical Name: Lomeguatrib
    CAS No.: 192441-08-0 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 2-Amino-6-[(4-bromo-2-thien... Quality Control & MSDS Files:
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    Brief introduction:

    Lomeguatrib (PaTrin-2) is a modified guanine base, which can repress the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) with an IC50 value of 6 nM. IC50 Value: 6 nM [1] Target: MGMT in vitro: PaTrin-2 effectively inactivated MGMT in MCF-7 cells (IC50 approximately 6 nM) and in xenografts there was comp...

  • Chemical Name: Indibulin
    CAS No.: 204205-90-3 Purity: Appearances:
    Brand: Synonyms: Nascapine; ZIO 301;D 24851;... Quality Control & MSDS Files:
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  • Chemical Name: Exemestane
    CAS No.: 107868-30-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: FCE 24304;EXE; (8R,9S,10R,1... Quality Control & MSDS Files:
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    Brief introduction:

    Exemestane(FCE 24304) is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively. Target: Aromatase Approved: October 2005 Exemestane competitively inhibits and time-dependently inactivates of human placental aromatase with Ki of 4.3 nM.

  • Chemical Name: Benoxaprofen
    CAS No.: 51234-28-7 Purity: Appearances:
    Brand: Synonyms: Oraflex; 2-(4-Chlorophenyl)... Quality Control & MSDS Files:
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  • Chemical Name: NKP608
    CAS No.: 177707-12-9 Purity: Appearances: Light yellow to yellow solid
    Brand: Synonyms: (2R,4S)-N-[1-[3,5-Bis(trifl... Quality Control & MSDS Files:
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    Brief introduction:

    NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.

  • Chemical Name: Lasofoxifene (Tartrate)
    CAS No.: 190791-29-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (5R,6S)-5,6,7,8-Tetrahydro-... Quality Control & MSDS Files:
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  • Chemical Name: Roflumilast
    CAS No.: 162401-32-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 3-(Cyclopropylmethoxy)-N-(3... Quality Control & MSDS Files:
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    Brief introduction:

    Roflumilast(Daliresp) is a drug which acts as a selective, long-acting inhibitor of the enzyme PDE-4 with an IC50 of 0.8 nM.

  • Chemical Name: Loteprednol Etabonate
    CAS No.: 82034-46-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (8S,9S,10R,11S,13S,14S,17R)... Quality Control & MSDS Files:
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    Brief introduction:

    Loteprednol Etabonate is an anti-inflammatory corticosteroid used in optometry and ophthalmology. IC50 Value: Target: Glucocorticoid Receptor in vitro: in vivo: Intravenous administration of loteprednol etabonate (5 mg/kg) to dogs revealed a terminal half-life of 2.8 h, a volume of distribution of 3.7 L/kg, and a total body cleara...

  • Chemical Name: Nepafenac
    CAS No.: 78281-72-8 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: AHR 9434;AL 6515;Nevanac;AH... Quality Control & MSDS Files:
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    Brief introduction:

    Nepafenac(AHR 9434; AL 6515; Nevanac) is a selective COX-2 inhibitor; is prodrug of Amfenac. IC50 value: Target: COX-2 Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.

  • Chemical Name: Empagliflozin
    CAS No.: 864070-44-0 Purity: Appearances: White to off-white solid
    Brand: Synonyms: BI-10773;BI 10773;BI10773; ... Quality Control & MSDS Files:
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    Brief introduction:

    Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. IC50 value: 3.1 nM [1] Target: SGLT-2 Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), which is found almost exclusively in the proximal tubules of nephronic...

  • Chemical Name: Eltrombopag
    CAS No.: 496775-61-2 Purity: Appearances: Off-white to orange Solid
    Brand: Synonyms: SB-497115;SB-497115-GR;SB49... Quality Control & MSDS Files:
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    Brief introduction:

    Eltrombopag(SB-497115) is a new, orally active thrombopoietin-receptor (c-mpl) agonist that stimulates thrombopoiesis. IC50 Value: 0.27 uM (EC50 in murine BAF3 cells) [1] Target: thrombopoietin-receptor (c-mpl) Potential advantages of eltrombopag may include a sustained platelet response and a good tolerability profile. in vitro: E...

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