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Apichem Chemical Technology Co., Ltd.

41

Basic Information

Company Name:Apichem Chemical Technology Co., Ltd.

Business Type:Chemical manufacturer

Total NO.Employees:

Country/Region:China

Certificates:

Year Established:

Introduction of Apichem Chemical Technology Co., Ltd.

Web: www.apichem.net TEL:+86 (21) 6199-2249 Fax:+86 (21) 5196-9751 Email:[email protected],[email protected]

Products of Apichem Chemical Technology Co., Ltd.

  • Chemical Name: Tirofiban
    CAS No.: 144494-65-5 Purity: Appearances:
    Brand: Synonyms: (2S)-2-(Butylsulfonylamino)... Quality Control & MSDS Files:
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    Brief introduction:

    Tirofiban(L700462;MK383) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist Target: integrin IIb/IIIa Tirofiban hydrochloride monohydrate blocks platelet aggregation and thrombus formation.

  • Chemical Name: Pantoprazole
    CAS No.: 102625-70-7 Purity: Appearances:
    Brand: Synonyms: Protonix;SKF96022; 6-(diflu... Quality Control & MSDS Files:
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    Brief introduction:

    Pantoprazole(SKF96022; Protonix) is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. IC50 value: Target: proton pump inhibitor

  • Chemical Name: Pimobendan
    CAS No.: 74150-27-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Vetmedin;Acardi;pimobendane... Quality Control & MSDS Files:
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    Brief introduction:

    Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM. Target: PDE3 Pimobendan exhibits selective inhibition of PDE III isolated from guinea pig cardiac muscle with IC50 of 0.32 uM compared to the inhibition of PDE I and PDE II (IC50s >30 μM).

  • Chemical Name: Zonisamide (sodium)
    CAS No.: 68291-98-5 Purity: Appearances:
    Brand: Synonyms: AD 810 sodium;CI 912 sodium... Quality Control & MSDS Files:
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    Brief introduction:

    Zonisamide sodium is a 1,2 benzisoxazole derivative and the first agent of this chemical class to be developed as an antiepileptic drug. Target: Calcium channel inhibitor; Sodium channel inhibitor Zonisamide sodium is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures for adul...

  • Chemical Name: Dienogest
    CAS No.: 65928-58-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 2-((8S,13S,14S,17R)-17-hydr... Quality Control & MSDS Files:
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    Brief introduction:

    Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis.

  • Chemical Name: Amprenavir
    CAS No.: 161814-49-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: [(3S)-Oxolan-3-yl] N-[(2S,3... Quality Control & MSDS Files:
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    Brief introduction:

    Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection. IC50 Value: 0.6 nM (Ki); Against wild-type clinical HIV isolates:14.6 +/- 12.5 ng/mL (mean +/- SD) [1]. Target: HIV protease in vitro: Amprenavir has an enzyme inhibition constant (Ki = 0.6 nM) that falls within the Ki range of the other prote...

  • Chemical Name: Tesmilifene
    CAS No.: 98774-23-3 Purity: Appearances:
    Brand: Synonyms: DPPE; 2-(4-benzylphenoxy)-N... Quality Control & MSDS Files:
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  • Chemical Name: Pergolide
    CAS No.: 66104-22-1 Purity: Appearances:
    Brand: Synonyms: 8beta-[(Methylthio)methyl]-... Quality Control & MSDS Files:
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    Brief introduction:

    Pergolide (Permax, Pergotoliderived) is an ergoline-based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease. Parkinson's disease is associated with low levels of the neurotransmitter dopamine in the brain. Pergolide has some of the same effects as dopamine in the body. In 2007, pergolide was with...

  • Chemical Name: Lomeguatrib
    CAS No.: 192441-08-0 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 2-Amino-6-[(4-bromo-2-thien... Quality Control & MSDS Files:
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    Lomeguatrib (PaTrin-2) is a modified guanine base, which can repress the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) with an IC50 value of 6 nM. IC50 Value: 6 nM [1] Target: MGMT in vitro: PaTrin-2 effectively inactivated MGMT in MCF-7 cells (IC50 approximately 6 nM) and in xenografts there was comp...

  • Chemical Name: Indibulin
    CAS No.: 204205-90-3 Purity: Appearances:
    Brand: Synonyms: Nascapine; ZIO 301;D 24851;... Quality Control & MSDS Files:
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    Brief introduction:

    Microtubule destabilizer that blocks tubulin polymerization (IC50 = 0.3 μM). Blocks cell cycle progression at metaphase and displays antitumor activity against a variety of malignancies in vitro (IC50 values ranging from 0.036 - 0.285 μM). Induces complete tumor remission in the Yoshida AH13 rat sarcoma model in vivo. Lacks neurotoxici...

  • Chemical Name: Exemestane
    CAS No.: 107868-30-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: FCE 24304;EXE; (8R,9S,10R,1... Quality Control & MSDS Files:
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    Brief introduction:

    Exemestane(FCE 24304) is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively. Target: Aromatase Approved: October 2005 Exemestane competitively inhibits and time-dependently inactivates of human placental aromatase with Ki of 4.3 nM.

  • Chemical Name: Benoxaprofen
    CAS No.: 51234-28-7 Purity: Appearances:
    Brand: Synonyms: Oraflex; 2-(4-Chlorophenyl)... Quality Control & MSDS Files:
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    Brief introduction:

    Benoxaprofen, also known as Benoxaphen, is a non-steroidal anti-inflammatory drug developed by Eli Lilly and Company. Lilly suspended sales of Oraflex in 1982 after reports from the British government and the U.S. Food and Drug Administration (FDA) of adverse effects and deaths linked to the drug.

  • Chemical Name: NKP608
    CAS No.: 177707-12-9 Purity: Appearances: Light yellow to yellow solid
    Brand: Synonyms: (2R,4S)-N-[1-[3,5-Bis(trifl... Quality Control & MSDS Files:
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    Brief introduction:

    NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.

  • Chemical Name: Lasofoxifene (Tartrate)
    CAS No.: 190791-29-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (5R,6S)-5,6,7,8-Tetrahydro-... Quality Control & MSDS Files:
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  • Chemical Name: Roflumilast
    CAS No.: 162401-32-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 3-(Cyclopropylmethoxy)-N-(3... Quality Control & MSDS Files:
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    Brief introduction:

    Roflumilast(Daliresp) is a drug which acts as a selective, long-acting inhibitor of the enzyme PDE-4 with an IC50 of 0.8 nM.

  • Chemical Name: Loteprednol Etabonate
    CAS No.: 82034-46-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (8S,9S,10R,11S,13S,14S,17R)... Quality Control & MSDS Files:
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    Brief introduction:

    Loteprednol Etabonate is an anti-inflammatory corticosteroid used in optometry and ophthalmology. IC50 Value: Target: Glucocorticoid Receptor in vitro: in vivo: Intravenous administration of loteprednol etabonate (5 mg/kg) to dogs revealed a terminal half-life of 2.8 h, a volume of distribution of 3.7 L/kg, and a total body cleara...

  • Chemical Name: Nepafenac
    CAS No.: 78281-72-8 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: AHR 9434;AL 6515;Nevanac;AH... Quality Control & MSDS Files:
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    Brief introduction:

    Nepafenac(AHR 9434; AL 6515; Nevanac) is a selective COX-2 inhibitor; is prodrug of Amfenac. IC50 value: Target: COX-2 Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.

  • Chemical Name: Empagliflozin
    CAS No.: 864070-44-0 Purity: Appearances: White to off-white solid
    Brand: Synonyms: BI-10773;BI 10773;BI10773; ... Quality Control & MSDS Files:
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    Brief introduction:

    Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. IC50 value: 3.1 nM [1] Target: SGLT-2 Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), which is found almost exclusively in the proximal tubules of nephronic...

  • Chemical Name: Eltrombopag
    CAS No.: 496775-61-2 Purity: Appearances: Off-white to orange Solid
    Brand: Synonyms: SB-497115;SB-497115-GR;SB49... Quality Control & MSDS Files:
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    Brief introduction:

    Eltrombopag(SB-497115) is a new, orally active thrombopoietin-receptor (c-mpl) agonist that stimulates thrombopoiesis. IC50 Value: 0.27 uM (EC50 in murine BAF3 cells) [1] Target: thrombopoietin-receptor (c-mpl) Potential advantages of eltrombopag may include a sustained platelet response and a good tolerability profile. in vitro: E...

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