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Chemical Name:
PEAQX
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CAS No.:
459836-30-7
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Synonyms: NVP-AAM077 |
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Brief introduction:
NVP-AAM077 inhibited progenitor cells proliferation in the subventricular zone and dentate gyrus and reduced the survival of newborn cells in the dentate gyrus in the adult mice.
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Chemical Name:
LY2857785
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CAS No.:
1619903-54-6
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: LY 2857785;LY-2857785; (1r,... |
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Brief introduction:
LY2857785 is a type I reversible and competitive ATP kinase inhibitor against <b>CDK9</b> (<b>IC<sub>50</sub></b> 11 nM) and other transcription kinases <b>CDK8</b> (<b>IC<sub>50</sub></b> 16 nM), and <b>CDK7</b> (<b>IC<sub>50</sub></b> 246 nM).
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Chemical Name:
(R)-(+)-Etomoxir sodium salt
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CAS No.:
828934-41-4
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: (+)-Etomoxir sodium salt; s... |
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Brief introduction:
(R)-(+)-Etomoxir (sodium salt) is a potent inhibitor of carnitine palmitoyltransferase I (CPT1); inhibits β-oxidation in mitochondria; shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells.
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Chemical Name:
IM-12
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CAS No.:
1129669-05-1
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Purity: |
Appearances: Light yellow to yellow Solid |
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Synonyms: IM 12;IM12; 3-((4-fluorophe... |
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Brief introduction:
IM-12 is an inhibitor of <b>GSK-3β</b>, with an <b>IC<sub>50</sub></b> of 53 nM, and also enhances Wnt signalling.
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Chemical Name:
Nexturastat A
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CAS No.:
1403783-31-2
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: 4-((1-butyl-3-phenylureido)... |
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Description
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Chemical Name:
kb-NB77-78
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CAS No.:
1350622-33-1
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Purity: |
Appearances: Light yellow to yellow Solid |
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Synonyms: 9-((tert-butyldimethylsilyl... |
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Brief introduction:
kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).
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Chemical Name:
MMAD (hydrochloride)
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CAS No.:
173441-26-4
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Purity: |
Appearances: White to off-white solid |
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Synonyms: Demethyldolastatin 10 hydro... |
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Brief introduction:
A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).
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Chemical Name:
HG6-64-1
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CAS No.:
1315329-43-1
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Purity: |
Appearances: Light yellow to yellow Solid |
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Synonyms: HG-6-64-1;HG 6-64-1; (E)-N-... |
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Brief introduction:
HG6-64-1 is a potent and selective <b>B-Raf</b> inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a <b>IC<sub>50</sub></b> of 0.09 μM on B-raf V600E transformed Ba/F3 cells.
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Chemical Name:
Dictamnine
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CAS No.:
484-29-7
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Purity: |
Appearances: Light yellow to yellow Solid |
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Synonyms: 4-Methoxyfuro[2,3-b]quinoli... |
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Brief introduction:
Dictamnine (Dictamine) has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; A natural plant product has been reported to have antimicrobial activity against bacteria and fungi.
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Target:
Dictamnine has antimicrobial activities against the model fungus Saccharomyces cerevisiae, with a min...
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Chemical Name:
RGDS peptide
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CAS No.:
91037-65-9
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: RGDS peptide;Fibronectin In... |
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Brief introduction:
Arg-Gly-Asp-Ser(RGDS peptide) is an integrin binding sequence that inhibits integrin receptor function; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9.
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Chemical Name:
Defactinib
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CAS No.:
1073154-85-4
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: VS-6063;VS6063;VS 6063; N-m... |
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Brief introduction:
Defactinib is a novel <b>FAK</b> inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
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Chemical Name:
Ozanimod (RPC1063)
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CAS No.:
1306760-87-1
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: RPC-1063 |
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Brief introduction:
Ozanimod is a potent and selective <b>S1P<sub>1</sub></b> and <b>S1P<sub>5</sub> receptor</b> agonist with <b>EC<sub>50</sub></b>s of 410±160 pM and 11±4.3 nM in [<sup>35</sup>S]-GTPγS binding, respectively.
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Chemical Name:
YH239-EE
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CAS No.:
1364488-67-4
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: YH 239-EE;YH 239 EE; ethyl ... |
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Brief introduction:
Description
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Chemical Name:
PI-1840
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CAS No.:
1401223-22-0
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: PI 1840;PI1840; N-isopropyl... |
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Brief introduction:
Description
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Chemical Name:
INK1117
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CAS No.:
1268454-23-4
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Purity: |
Appearances: White to gray Solid |
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Synonyms: Serabelisib;INK1117 |
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Brief introduction:
MLN1117 is a selective <b>p110α</b> inhibitor with an <b>IC<sub>50</sub></b> of 15 nM.
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Chemical Name:
NVP-QAV680
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CAS No.:
872365-16-7
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Synonyms: NVP-QAV-680 |
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Brief introduction:
NVP-QAV-680 is a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases. A highly selective compound, it has low nM functional potency for inhibition of CRTh2 driven human eosinophil and Th2 lymphocyte activation in vitro.
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Chemical Name:
Rostafuroxin (PST 2238)
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CAS No.:
156722-18-8
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: PST-2238;PST 2238;PST2238; ... |
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Brief introduction:
Na+/K+ ATPase modulator. Inhibits the Normalizes renal Na+/K+ ATPase pump function in mutant adducin- and endogenous ouabain-dependent forms of hypertension. Reduces blood pressure in Milan hypertensive rats. Controls mania-like behaviors in Myshkin mice having a Na+/K+ ATPase α3 subunit mutation. Antagonizes the effects of Ouabain (Ca...
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Chemical Name:
GNE-9605
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CAS No.:
1536200-31-3
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: GNE 9605;GNE9605;N2-(5-chlo... |
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Brief introduction:
GNE-9605 is a highly potent and selective <b>leucine-rich repeat kinase 2 (LRRK2)</b> inhibitor with <b>K<sub>i</sub></b> and <b>IC50</b> of 2 nM and 19 nM, respectively.
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Chemical Name:
CDK7-IN-1
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CAS No.:
1604810-84-5
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: THZ2; THZ 2; THZ-2. |
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Brief introduction:
THZ2 is a potent and selective <b>CDK7</b> inhibitor with <b>IC<sub>50</sub></b> of 13.9 nM.
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Chemical Name:
THZ2
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CAS No.:
1604810-84-5
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: THZ2; THZ 2; THZ-2. |
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Brief introduction:
THZ2 is a potent and selective <b>CDK7</b> inhibitor with <b>IC<sub>50</sub></b> of 13.9 nM.
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