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AdooQ BioScience, LLC

4521

Basic Information

Company Name:AdooQ BioScience, LLC

Business Type:Chemical manufacturer since 2006

Total NO.Employees:

Country/Region:USA

Certificates:

Year Established: 2006

Introduction of AdooQ BioScience, LLC

AdooQ BioScience is a supplier of biochemicals located in irvine, CA since 2006. In past five years, we have been a renowned name engaged in manufacturing and supplying small molecule inhibitors including kinase inhibitors on kinds of signal pathway, such as PI3K, AKT, HDAC, MARP etc.

Web: www.adooq.com TEL:855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) Fax:866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada) Email:[email protected]

Products of AdooQ BioScience, LLC

  • Chemical Name: T-5224
    CAS No.: 530141-72-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: T5224;T 5224; 3-(5-(4-(cycl... Quality Control & MSDS Files:
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    Brief introduction:

    T-5224 is a selective inhibitor of c-Fos/activator protein-1.

  • Chemical Name: CB-839
    CAS No.: 1439399-58-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 2-(pyridin-2-yl)-N-(5-(4-(6... Quality Control & MSDS Files:
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    Brief introduction:

    CB-839 an is orally bioavailable inhibitor of glutaminase, with potential antineoplastic activity.

  • Chemical Name: INH1
    CAS No.: 313553-47-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: IBT13131; N-(4-(2,4-dimethy... Quality Control & MSDS Files:
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    Brief introduction:

    INH1 is a Hec1 inhibitor. It binds Hec1, inhibiting its association with Nek2 and kinetochores.

  • Chemical Name: EHT 1864
    CAS No.: 754240-09-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: EHT1864;EHT-1864; 2-(morpho... Quality Control & MSDS Files:
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    Brief introduction:

    EHT 1864 is an antiproliferative chemical shown to inhibit Rac family GTPases.

  • Chemical Name: Z-VAD-FMK
    CAS No.: 187389-52-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Z-Val-Ala-Asp(OMe)-FMK Quality Control & MSDS Files:
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    Brief introduction:

    Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0.0015 - 5.8 mM). Active in vivo.

  • Chemical Name: Eluxadoline
    CAS No.: 864821-90-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: JNJ 27018966;JNJ27018966;JN... Quality Control & MSDS Files:
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    Brief introduction:

    Eluxadoline is a novel, orally-active drug approved for the treatment of diarrhea and abdominal pain in individuals with diarrhea-predominant irritable bowel syndrome (IBS-D).

  • Chemical Name: Melphalan
    CAS No.: 148-82-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-[Bis(2-chloroethyl)amino]... Quality Control & MSDS Files:
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    Brief introduction:

    Melphalan is a cytotoxic drug used to treat multiple myeloma. Phenylamine derivative of mechorethamine.

  • Chemical Name: Thiotepa
    CAS No.: 52-24-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N,N',N''-Triethylenethiopho... Quality Control & MSDS Files:
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    Brief introduction:

    Thiotepa is a polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity.

  • Chemical Name: PF6-AM
    CAS No.: 1268491-69-5 Purity: Appearances:
    Brand: Synonyms: Peroxyfluor 6 acetoxymethyl... Quality Control & MSDS Files:
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    Brief introduction:

    PF6-AM is a new selective fluorescent indicator for hydrogen peroxide (H(2)O(2)), a tool to help discover new redox chemistry in biological systems.

  • Chemical Name: XEN445
    CAS No.: 1515856-92-4 Purity: Appearances: nigger-brown Solid
    Brand: Synonyms: XEN 445;XEN-445; (S)-2-(3-(... Quality Control & MSDS Files:
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    Brief introduction:

    XEN445 is a potent and selective EL inhibitor(IC50=0.237 uM), that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice.

  • Chemical Name: Atosiban
    CAS No.: 90779-69-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Tractocile;Antocin;RW22164;... Quality Control & MSDS Files:
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    Brief introduction:

    Atosiban is a peptide Oxytocin Receptor Inhibitor.

  • Chemical Name: GBR 12935
    CAS No.: 76778-22-8 Purity: Appearances:
    Brand: Synonyms: GBR12935;GBR-12935; 1-(2-(b... Quality Control & MSDS Files:
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    Brief introduction:

    GBR 12935 is a potent, and selective dopamine reuptake inhibitor. IC50 value: Target: dopamine reuptake inhibitor in vitro: The calculated Kd of [3H]GBR-12935 binding to CYP2D6 was 42.2 nM, indicating that GBR-12935 has a high affinity for CYP2D6.

  • Chemical Name: GDC-0834
    CAS No.: 1133432-46-8 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: GDC 0834 Racemate;GDC0834 R... Quality Control & MSDS Files:
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    Brief introduction:

    GDC-0834 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), investigated as a potential treatment for rheumatoid arthritis.

  • Chemical Name: CID 797718
    CAS No.: 370586-05-3 Purity: Appearances: Light brown to brown Solid
    Brand: Synonyms: CID 797718; CID-797718; CID... Quality Control & MSDS Files:
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    Brief introduction:

    CID797718 is a structural analog of CID755673 (Adooq Catalog No. A13804). It was a 10-time less potent PKD1 inhibitor with an IC50 value of 7.0 +/-0.8 uM.

  • Chemical Name: GBR-12935 2HCl
    CAS No.: 67469-81-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: GBR12935 dihydrochloride;GB... Quality Control & MSDS Files:
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    Brief introduction:

    GBR-12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor.

  • Chemical Name: PD 0332991 Isethionate
    CAS No.: 827022-33-3 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: PD0332991 isethionate;PD-03... Quality Control & MSDS Files:
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    Brief introduction:

    PD 0332991 Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM respectively.

  • Chemical Name: CID 755673
    CAS No.: 521937-07-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: CID 755673;CID-755673; 7-hy... Quality Control & MSDS Files:
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    Brief introduction:

    CID755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM; exhibits selective PKD1 inhibition when compared with AKT, PLK1, CAK, CAMKIIα, and PKC isoforms. IC50 value: 182 nM [1] Target: PKD in vitro: In cell-based assays, CID755673 blocked phorbol ester-induced endogenous PKD1 activatio...

  • Chemical Name: IWR-1-endo
    CAS No.: 1127442-82-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: endo-IWR 1;IWR-1-endo;IWR1;... Quality Control & MSDS Files:
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    Brief introduction:

    IWR-1-endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 value of 180 nM. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription.<br>

  • Chemical Name: PI-3065
    CAS No.: 955977-50-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PI3065;PI 3065; 4-(6-((4-(c... Quality Control & MSDS Files:
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    Brief introduction:

    PI-3065 is a small molecule and selective inhibitor of p110δ kinase with an Ki value of 1.5nM and IC50 value of 5nM

  • Chemical Name: Obeticholic Acid
    CAS No.: 459789-99-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Obeticholic acid;6-ECDCA;6-... Quality Control & MSDS Files:
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    Brief introduction:

    Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM