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Active Biopharma Corp

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Basic Information

Company Name:Active Biopharma Corp

Business Type:Chemical manufacturer

Total NO.Employees:

Country/Region:China

Certificates:

Year Established:

Introduction of Active Biopharma Corp

Web: www.activebiopharma.com TEL:+86 (571) 8161-2335 Fax: Email:[email protected]

Products of Active Biopharma Corp

  • Chemical Name: Ketorolac
    CAS No.: 74103-06-3 Purity: Appearances:
    Brand: Synonyms: Acular LS;RS37619;Sprix;Tor... Quality Control & MSDS Files:
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    Brief introduction:

    Ketorolac(RS37619), a non-selective COX inhibitor, is a non-steroidal anti-inflammatory drug.

  • Chemical Name: Naratriptan
    CAS No.: 121679-13-8 Purity: Appearances:
    Brand: Synonyms: N-Methyl-2-[3-(1-methylpipe... Quality Control & MSDS Files:
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    Brief introduction:

    Naratriptan is a selective 5-HT1 receptor subtype agonist and is a triptan drug that is used for the treatment of migraine headaches. Target: 5-HT1 Receptor Naratriptan is a triptan drug marketed by GlaxoSmithKline and is used for the treatment of migraine headaches.

  • Chemical Name: Ketorolac (tromethamine salt)
    CAS No.: 74103-07-4 Purity: Appearances: white Solid
    Brand: Synonyms: Ketorolac tris salt;Toradol... Quality Control & MSDS Files:
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    Brief introduction:

    Ketorolac (Ketorolac tromethamine, Toradol) is a non-selective COX inhibitor with strong analgesic activity. Target: COX Ketorolac or ketorolac tromethamine is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives, used as an analgesic.

  • Chemical Name: Stavudine
    CAS No.: 3056-17-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 2',3'-Didehydro-3'-deoxythy... Quality Control & MSDS Files:
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    Brief introduction:

    Stavudine is a nucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. Target: HIV RT; NRTIs Stavudine is a dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

  • Chemical Name: Naratriptan (hydrochloride)
    CAS No.: 143388-64-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N-Methyl-3-(1-methylpiperid... Quality Control & MSDS Files:
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    Brief introduction:

    Naratriptan hydrochloride is a selective 5-HT1 receptor subtype agonist and is a triptan drug that is used for the treatment of migraine headaches. Target: 5-HT1 Receptor Naratriptan is a triptan drug marketed by GlaxoSmithKline and is used for the treatment of migraine headaches.

  • Chemical Name: Delafloxacin
    CAS No.: 189279-58-1 Purity: Appearances:
    Brand: Synonyms: Delafloxacinum;RX-3341;WQ-3... Quality Control & MSDS Files:
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    Brief introduction:

    Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. IC50 Value: MICs ranging from 0.0078 to 0.125 micro g/ml for levofloxacin-resistant Streptococcus pneumoniae strains [1] Target: Antibacterial ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to th...

  • Chemical Name: CP-547632
    CAS No.: 252003-65-9 Purity: Appearances:
    Brand: Synonyms: 3-((4-bromo-2,6-difluoroben... Quality Control & MSDS Files:
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    Brief introduction:

    CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively).

  • Chemical Name: CHIR-98014
    CAS No.: 252935-94-7 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: CHIR98014;CHIR 98014; N2-(2... Quality Control & MSDS Files:
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    Brief introduction:

    CHIR-98014 is a selective GSK3 inhibitor with IC50s of 0.65 nM and 0.58 nM for GSK-3α and GSK-3β; potentiate insulin activation of glucose transport and utilization in vitro and in vivo. IC50 value: 0.65 nM/0.58 nM (GSK-3α/GSK-3β) [1] Target: GSK-3α/GSK-3β Exposure of insulin receptor–expressing CHO-IR cells or primary rat hepatocyt...

  • Chemical Name: RepSox
    CAS No.: 446859-33-2 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: E-616452;SJN 2511;E616452;S... Quality Control & MSDS Files:
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    Brief introduction:

    RepSox(E-616452; SJN 2511) is a potent and selective inhibitor of the TGFβR-1/ALK5 with IC50 of 23 nM and 4 nM for ATP binding to ALK5 and ALK5 autophosphorylation, respectively. IC50 Value: 23 nM Target: ALK5 in vitro: Pretreated MEFs with RepSox, applying the chemical for three days, and then removed it at the time of transduction...

  • Chemical Name: LDN193189
    CAS No.: 1062368-24-4 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: LDN 193189; LDN-193189; DM-... Quality Control & MSDS Files:
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    Brief introduction:

    LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. IC50 value: 5 nM/30 nM (ALK2/ALK3) [1] Target: ALK2/3 in vitro: LDN193189 potently inhibits BMP4-med...

  • Chemical Name: Telatinib
    CAS No.: 332012-40-5 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Bay 57-9352 Quality Control & MSDS Files:
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    Brief introduction:

    Telatinib (Bay 57-9352) is an orally active, small molecule inhibitor of <b>VEGFR2</b>, <b> VEGFR3</b>, <b>PDGFα</b>, and <b>c-Kit</b> with <b>IC<sub>50</sub></b>s of 6, 4, 15 and 1 nM, respectively.

  • Chemical Name: BI-D1870
    CAS No.: 501437-28-1 Purity: Appearances: White to off-white solid
    Brand: Synonyms: BI-D 1870; 2-((3,5-difluoro... Quality Control & MSDS Files:
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    Brief introduction:

    BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B.

  • Chemical Name: LY2109761
    CAS No.: 700874-71-1 Purity: Appearances: White to off-white solid
    Brand: Synonyms: LY 2109761;LY-2109761; 4-(2... Quality Control & MSDS Files:
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    Brief introduction:

    LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively; shown to negatively affect the phosphorylation of Smad2. IC50 value: 38 nM/300 nM(Ki, TβRI/II) [1] Target: TGF-β receptor type I/II in vitro: LY2109761 treatment induces a dose-dependent low-anchorage growth in...

  • Chemical Name: AMG 900
    CAS No.: 945595-80-2 Purity: Appearances: Light yellow to yellow solid
    Brand: Synonyms: AMG-900;AMG900; N-(4-((3-(2... Quality Control & MSDS Files:
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    Brief introduction:

    AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM; >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2.

  • Chemical Name: PHA-680632
    CAS No.: 398493-79-3 Purity: Appearances:
    Brand: Synonyms: PHA680632;PHA 680632; N-(2,... Quality Control & MSDS Files:
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    Brief introduction:

    PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.

  • Chemical Name: Alisertib
    CAS No.: 1028486-01-2 Purity: Appearances: Pink to red Solid
    Brand: Synonyms: MLN 8237;MLN8237;MLN-8237; ... Quality Control & MSDS Files:
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    Brief introduction:

    Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM; has >200-fold higher selectivity for Aurora A than Aurora B. IC50 Value: 1.2 nM (Aurora A) Target: Aurora A in vitro: MLN8237 (0.5 μM) treatment inhibits the phosphorylation of Aurora A in MM1.S and OPM1 cells, without affecting the Aurora B mediated histone ...

  • Chemical Name: Selumetinib
    CAS No.: 606143-52-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: AZD6244; Array142886; ARRY-... Quality Control & MSDS Files:
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    Brief introduction:

    Selumetinib (AZD6244; ARRY-142886) is a potent, highly selective MEK1 inhibitor with IC50 of 14 nM, also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. IC50 value: 14 nM [1] Target: MEK1 in vitro: ZD6244 is not competitive with ATP and inactivates the ERK1/2 phosphoryl...

  • Chemical Name: Navitoclax
    CAS No.: 923564-51-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: ABT-263;ABT 263;ABT263; (R)... Quality Control & MSDS Files:
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    Brief introduction:

    ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤1 nM. IC50 Value: ≤ 0.5 nM(Ki for Bcl-xL); ≤1 nM(Ki for Bcl-2); ≤1 nM(Ki for Bcl-w) Target: Bcl-2 Family in vitro: ABT-263 displays the protection afforded by overexpression of Bcl-2 or Bcl-xL with EC50 values of 60 nM and 20 nM, r...

  • Chemical Name: 1,3,6,8-Tetrabromopyrene
    CAS No.: 128-63-2 Purity: Appearances:
    Brand: Synonyms: 1,3,6,8-tetrabromopyrene Quality Control & MSDS Files:
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