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Background Information of BAY-1143572

BAY-1143572 is a potent and highly selective, oral PTEFb/CDK9 inhibitor. BAY-1143572 inhibits CDK9/CycT1 with an IC50 of 13 nM.

Solubility of BAY-1143572

Solubility Sources

Storage Condition of BAY-1143572

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MSDS Information

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Quality Control and Spectral Data

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Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage
Target CDK
Research Area

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase

Chemical Information

M.Wt Formula CAS No. Synonyms
387.43 C18H18FN5O2S

Structure Information of BAY-1143572

Smiles N=[[email protected]](CC1=CC(NC2=NC(C3=CC=C(F)C=C3OC)=NC=N2)=CC=C1)(C)=O
InChI InChI=1S/C18H18FN5O2S/c1-26-16-9-13(19)6-7-15(16)17-21-11-22-18(24-17)23-14-5-3-4-12(8-14)10-27(2,20)25/h3-9,11,20H,10H2,1-2H3,(H,21,22,23,24)/t27-/m1/s1

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Chemical and Physical Properties

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