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11beta-Hydroxyprogesterone

(CAS: 600-57-7)

Suppliers of 11beta-Hydroxyprogesterone

Company Name Email Tel Country
CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: >98% Brand: Chemscene

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: >98% Brand: MedChemExpress

Price and Availability: USD50/10mg (Get quote) USD110/50mg (Get quote)
Quality Control & MSDS Files: HNMR MSDS

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: >98% Brand: ChemExpress

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Background Information of 11beta-Hydroxyprogesterone

11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase; also activates human mineralocorticoid receptor in COS-7 cells with an ED50 of 10 nM. IC50 & Target: ED50: 10 nM (human mineralocorticoid receptor, COS-7 cell )[1] In Vitro: 11OHP displays agonist mineralocorticoid activity.

Solubility of 11beta-Hydroxyprogesterone

Solubility Sources
10 mM in DMSO CHEMSCENE, LLC
10 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of 11beta-Hydroxyprogesterone

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Others
Target Others
Research Area Cardiovascular Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase

Chemical Information

M.Wt Formula CAS No. Synonyms
330.46 C21H30O3 600-57-7 11β-Hydroxyprogesterone; (8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Structure Information of 11beta-Hydroxyprogesterone

Smiles C[[email protected]@]12[[email protected]]3([H])[[email protected]](CCC1=CC(CC2)=O)([H])[[email protected]@]4([H])[[email protected]@](C)([[email protected]@H](C(C)=O)CC4)C[[email protected]@H]3O
InChI InChI=1S/C21H30O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17-,18-,19+,20-,21+/m0/s1

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Chemical and Physical Properties

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