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RG-12525

(CAS: 120128-20-3)

Suppliers of RG-12525

Company Name Email Tel Country
CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD480/1mg () USD960/5mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD480/1mg () USD960/5mg ()

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD480/1mg () USD960/5mg ()

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Background Information of RG-12525

RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4; Also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 µM.

Solubility of RG-12525

Solubility Sources

Storage Condition of RG-12525

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MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways NF-κB Metabolic Enzyme/Protease Cell Cycle/DNA Damage GPCR/G Protein
Target PPAR Leukotriene Receptor Cytochrome P450
Research Area
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase

Chemical Information

M.Wt Formula CAS No. Synonyms
423.47 C25H21N5O2 120128-20-3 NID-525;NID525;NID 525;RG12525;RG 12525; 2-((4-((2-((1H-tetrazol-5-yl)methyl)benzyl)oxy)phenoxy)methyl)quinoline

Structure Information of RG-12525

Smiles C1(COC2=CC=C(OCC3=CC=CC=C3CC4=NN=NN4)C=C2)=NC5=CC=CC=C5C=C1
InChI InChI=1S/C25H21N5O2/c1-2-7-20(19(6-1)15-25-27-29-30-28-25)16-31-22-11-13-23(14-12-22)32-17-21-10-9-18-5-3-4-8-24(18)26-21/h1-14H,15-17H2,(H,27,28,29,30)

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Chemical and Physical Properties

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Reference

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