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ON123300

(CAS: 1357470-29-1)

Suppliers of ON123300

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Apexbio Technology LLC [email protected]bt.com +1-832-696-8203 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD144/5mg () USD216/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD144/5mg () USD216/10mg ()
Quality Control & MSDS Files: NP-HPLC HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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ProbeChem [email protected] 86-21-80183644

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD144/5mg () USD216/10mg ()

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Background Information of ON123300

Leukemia. 2016 Jan;30(1):86-93. Cancer Res. 2016 Mar 1;76(5):1225-36. Mol Cancer Ther. 2014 May;13(5):1105-16.

Solubility of ON123300

Solubility Sources
10 mM in DMSO CHEMSCENE, LLC
10 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of ON123300

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[NP-HPLC] [HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage
Target CDK
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
ON123300 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
429.52 C24H27N7O 1357470-29-1 ON 123300;ON-123300; 8-cyclopentyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carbonitrile

Structure Information of ON123300

Smiles N#CC1=CC2=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=C2N(C5CCCC5)C1=O
InChI InChI=1S/C24H27N7O/c1-29-10-12-30(13-11-29)20-8-6-19(7-9-20)27-24-26-16-18-14-17(15-25)23(32)31(22(18)28-24)21-4-2-3-5-21/h6-9,14,16,21H,2-5,10-13H2,1H3,(H,26,27,28)

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Chemical and Physical Properties

Appearance:Off-white to orange Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,29 mg/mL(67.51 mM);In vitro:Water,Insoluble;In vitro: Ethanol,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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