• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

Naquotinib

(CAS: 1448232-80-1)

Suppliers of Naquotinib

Company Name Email Tel Country
BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: ≥98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD132/1mg () USD420/5mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD132/1mg () USD420/5mg ()

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD132/1mg () USD420/5mg ()

Shanghai XingMo Biotechnology Co., Ltd. [email protected] 13524779951 CHINA

Fax: Purity: > 98% Brand: X-MoBio

Price and Availability: USD1500/1g (In stock)

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of Naquotinib

Naquotinib (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; with IC50s of 8-33 nM toward EGFR mutants and 230 nM for EGFR.

Solubility of Naquotinib

Solubility Sources
DMSO CHEMSCENE, LLC
DMSO MedChemexpress Co., Ltd.

Storage Condition of Naquotinib

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways JAK/STAT Signaling Protein Tyrosine Kinase/RTK
Target EGFR
Research Area Cancer
Indications Advanced Non-small Cell Lung Cancer (NSCLC)

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Naquotinib Novartis Pharmaceuticals Advanced Non-small Cell Lung Cancer (NSCLC) 2014/4/07 2016/9/01 Phase 2 Clinical
Naquotinib - Phase 3

Chemical Information

M.Wt Formula CAS No. Synonyms
562.7063 C30H42N8O3 1448232-80-1 ASP8273

Structure Information of Naquotinib

Smiles O=C(C1=NC(CC)=C(O[[email protected]]2CN(C(C=C)=O)CC2)N=C1NC3=CC=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)N
InChI InChI=1S/C30H42N8O3/c1-4-25-30(41-24-12-15-38(20-24)26(39)5-2)34-29(27(33-25)28(31)40)32-21-6-8-22(9-7-21)36-13-10-23(11-14-36)37-18-16-35(3)17-19-37/h5-9,23-24H,2,4,10-20H2,1,3H3,(H2,31,40)(H,32,34)/t24-/m1/s1

Related Products

Other Form Products of Naquotinib

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
Ginsenoside Rh2 78214-33-2 C36H62O8 7
Mutated EGFR-IN-1 1421372-66-8 C25H31N7O 7
AZD-9291 (mesylate) 1421373-66-1 C29H37N7O5S 6
Mutant EGFR inhibitor 1421373-62-7 C27H30ClN7O2 6
AZD-9291 1421373-65-0 C28H33N7O2 18
WHI-P180 (hydrochloride) 153437-55-9 C16H16ClN3O3 5
WHI-P180 211555-08-7 C16H15N3O3 7
Gefitinib (hydrochloride) 184475-55-6 C22H25Cl2FN4O3 7
Erlotinib (mesylate) 248594-19-6 C23H27N3O7S 5
BGB-102 807640-87-5 C22H25BrN4O2 5
Poziotinib 1092364-38-9 C23H21Cl2FN4O3 12
CO-1686 (hydrobromide) 1446700-26-0 C27H29BrF3N7O3 11
CO-1686 1374640-70-6 C27H28F3N7O3 12
CNX-2006 1375465-09-0 C26H27F4N7O2 10
PD168393 194423-15-9 C17H13BrN4O 13
AG 18 118409-57-7 C10H6N2O2 16
Afatinib (dimaleate) 850140-73-7 C32H33ClFN5O11 11
Chrysophanol 481-74-3 C15H10O4 19
AG-1478 153436-53-4 C16H14ClN3O2 12
Mubritinib 366017-09-6 C25H23F3N4O2 24

Recommended Products in the Same Indication

Name CAS Formula Suppliers

Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy Naquotinib | Naquotinib IC50 | Naquotinib price | Naquotinib cost | Naquotinib solubility | Naquotinib purchase | Naquotinib manufacturer | Naquotinib research buy | Naquotinib order | Naquotinib MSDS | Naquotinib chemical structure | Naquotinib Storage condition | Naquotinib molecular weight | Naquotinib mw | Naquotinib datasheet | Naquotinib supplier | Naquotinib cell line | Naquotinib NMR | Naquotinib MS | Naquotinib IR | Naquotinib solubility | Naquotinib Safe information | Naquotinib Qc and Spectral Information | Naquotinib Clinical Information | Naquotinib Clinical Trial | Naquotinib Route of Synthesis | Naquotinib storage condition | Naquotinib diseases and conditions | Naquotinib flash point | Naquotinib boiling point | Naquotinib melting point | Naquotinib storage condition | Naquotinib brand