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Nepicastat (hydrochloride)

(CAS: 170151-24-3)

Suppliers of Nepicastat (hydrochloride)

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

Fax: Purity: Brand:

Price and Availability: USD250/10mg (In stock) USD750/50mg (In stock)

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Price and Availability: USD48/5mg () USD80/10mg () USD240/50mg ()

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD119/5mg (In stock) USD224/10mg (In stock) USD1729/200mg (In stock)

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

Price and Availability: USD3380/1g ()

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 0.98 Brand: BOC Sciences

Price and Availability: USD198/50mg (In stock)

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD84/5mg () USD144/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD84/5mg () USD144/10mg ()
Quality Control & MSDS Files: LCMS HNMR

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Price and Availability: USD255/5mg () USD1455/50mg ()

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD170/5mg (In stock) USD320/10mg (In stock) USD970/50mg (In stock) USD2470/200mg (In stock)
Quality Control & MSDS Files: HNMR HPLC HPLC HNMR HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD84/5mg () USD144/10mg ()

Sigma-Aldrich, Inc. [email protected] +86 (21) 6141-5566 / 800-819-3336 USA

Fax: Purity: Brand:

Price and Availability: USD81/5mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD97/10mg () USD288/50mg ()

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Background Information of Nepicastat (hydrochloride)

Solubility of Nepicastat (hydrochloride)

Solubility Sources
in DMSO > 10 mM CHEMSCENE, LLC
in DMSO > 10 mM MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 66 mg/mL (198.9 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of Nepicastat (hydrochloride)

Storage Condition Sources
4°C MedChemexpress Co., Ltd.

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease
Target Dopamine β-hydroxylase
Research Area Cardiovascular Disease
Indications Cocaine addiction Post traumatic stress disorder

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Nepicastat (hydrochloride) National Institute on Drug Abuse Cocaine addiction 2013/4/30 2014/8/31 Phase 2 Clinical
Nepicastat (hydrochloride) Biotie Therapies AG Post traumatic stress disorder 2008/6/30 2009/11/01 Phase 2 Clinical
Nepicastat (hydrochloride) Tuscaloosa Research and Education Advancement Corporation Post traumatic stress disorder 2009/4/30 2012/9/30 Phase 2 Clinical
Nepicastat (hydrochloride) Biotie Therapies AG Cocaine addiction 2008/6/30 Phase 2 Clinical
Nepicastat (hydrochloride) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
331.8117 C14H16ClF2N3S 170151-24-3 SYN-117 hydrochloride;RS-25560-197 hydrochloride

Structure Information of Nepicastat (hydrochloride)

Smiles FC1=CC(F)=C2CC[[email protected]@H](CC2=C1)N3C(CN)=CNC3=S.Cl
InChI InChI=1S/C14H15F2N3S.ClH/c15-9-3-8-4-10(1-2-12(8)13(16)5-9)19-11(6-17)7-18-14(19)20;/h3,5,7,10H,1-2,4,6,17H2,(H,18,20);1H/t10-;/m0./s1

Related Products

Other Form Products of Nepicastat (hydrochloride)

Name CAS Formula Suppliers
Nepicastat 173997-05-2 C14H15F2N3S 5
Nepicastat (R enantiomer hydrochloride) 195881-94-8 C14H16ClF2N3S 3

Recommended Products in Same Target

Name CAS Formula Suppliers
Nepicastat 173997-05-2 C14H15F2N3S 5

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Nepicastat 173997-05-2 C14H15F2N3S 5
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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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