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SNS-032

(CAS: 345627-80-7)

Suppliers of SNS-032

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

Fax: Purity: Brand:

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Apichem Chemical Technology Co., Ltd. [email protected],[email protected] +86 (21) 6199-2249 China

Fax: +86 (21) 5196-9751Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

Fax: 408-493-1801Purity: Brand:

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD50/5mg () USD70/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD50/5mg () USD70/10mg ()
Quality Control & MSDS Files: LCMS NP-HPLC HNMR MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Quality Control & MSDS Files: CoA MSDS

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD110/5mg (In stock) USD170/10mM/1mLIn DMSO (In stock) USD570/50mg (In stock) USD1670/200mg (In stock)
Quality Control & MSDS Files: HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD50/5mg () USD70/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD38/5mg () USD75/10mg () USD171/50mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: #99 % Brand: Tocris

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Background Information of SNS-032

SNS-032(BMS-387032) is a potent inhibitor of cyclin-dependent kinases (cdks) 9, 2 and 7 (IC50 values are 4, 38 and 62 nM respectively).

Solubility of SNS-032

Solubility Sources
DMSO ≥73mg/mL Water <1.2mg/mL Ethanol ≥73mg/mL MedChemexpress Co., Ltd.
Soluble in DMSO, not in water MedKoo Biosciences, Inc.
DMSO 76 mg/mL (199 mM) ; Water <1 mg/mL (<1 mM) ; Ethanol <1 mg/mL (<1 mM) Selleck Chemicals LLC
Soluble to 50 mM in DMSO Tocris Bioscience Inc.

Storage Condition of SNS-032

Storage Condition Sources
Storage condition:Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Stock solution storage:0 - 4 C for short term (days to weeks), or -20 C for long term (months). Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. MedKoo Biosciences, Inc.
Store at -20°C Tocris Bioscience Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.
MedKoo Biosciences, Inc.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [NP-HPLC] [HNMR] MedChemexpress Co., Ltd.
[CoA] MedKoo Biosciences, Inc.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage
Target CDK
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
SNS-032 - Discontinued
SNS-032 - Phase 1

Chemical Information

M.Wt Formula CAS No. Synonyms
380.53 C17H24N4O2S2 345627-80-7 BMS-387032;SNS 032;SNS032;BMS 387032;BMS387032; N-(5-(((5-(tert-butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide

Structure Information of SNS-032

Smiles CC(C)(C1=CN=C(CSC2=CN=C(NC(C3CCNCC3)=O)S2)O1)C
InChI InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)

Related Products

Other Form Products of SNS-032

Name CAS Formula Suppliers
BA 2737 4292-56-2 C13H12N2O5 2
2-Pentenoic acid, 4-amino-5-[(3S)-2-oxo-3-pyrrolidinyl]-, ethyl ester, (2E,4S)- 328086-61-9 C11H18N2O3 1
Chryseno[2,3-d][1,3]dioxole-2,7(4aH,5H)-dione, 4b,6,6a,7a,10a,11,11a,11b,12,13-decahydro-5-hydroxy-7a-(hydroxymethyl)-4a,6a-dimethyl-9-propyl-, (4aR,4bS,5S,6aS,7aR,10aR,11aS,11bS)- 1040085-99-1 C25H34O6 3
2-Piperidinecarboxylic acid, 4-methyl-, ethyl ester, (2R-cis)- 79199-61-4 C9H17NO2 4
21-Desacetyldeflazacort 13649-57-5 C23H29NO5 4
L 601920-0 20231-57-6 C25H40O3 4
Dolutegravir intermediate-1 1335210-23-5 C13H17NO8 5
SR 49498 748812-53-5 C25H30N6O2 3
2-(1-Methylethoxy)-1,3-bis(1-methylethyl)benzene 141214-18-8 C15H24O 2
3-Pyridinecarboxamide, 5-(4-butoxy-3-chlorophenyl)-N-[[2-(4-morpholinyl)-3-pyridinyl]methyl]- 1266212-81-0 C26H29ClN4O3 3

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Chemical and Physical Properties

Appearance:light yellow to khaki Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,76 mg/mL(199.72 mM);In vitro:Water,Insoluble;In vitro:Ethanol,Insoluble;In vivo:Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):30% PEG400+0.5% Tween80+5% propylene glycolFor best result
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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