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(CAS: 306974-70-9)

Suppliers of GW-1100

Company Name Email Tel Country
Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD71/5mg () USD134/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD71/5mg () USD134/10mg ()
Quality Control & MSDS Files: MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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ProbeChem [email protected] 86-21-80183644

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD71/5mg () USD134/10mg ()

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Background Information of GW-1100

GW 1100 is a selective antagonist of GPR40-mediated Ca2+ elevations in HEK293 cells stimulated by GW 9508 (an agonist of both GPR40 and GPR120, another GPCR activated by long chain fatty acids) or linoleic acid with a pIC50 value equal to 5.99. IC50 value: Target: GPR40 GPR40 is a G protein-coupled receptor (GPCR) that is activated by saturated and unsaturated long chain fatty acids.

Solubility of GW-1100

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of GW-1100

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways GPCR/G Protein
Target GPR40
Research Area Endocrinology

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
GW-1100 - Not Found
GW-1100 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
520.58 C27H25FN4O4S 306974-70-9 GW1100;GW1100; ethyl 4-(5-((2-ethoxypyrimidin-5-yl)methyl)-2-((4-fluorobenzyl)thio)-4-oxopyrimidin-1(4H)-yl)benzoate

Structure Information of GW-1100

Smiles O=C1C(CC2=CN=C(N=C2)OCC)=CN(C(SCC3=CC=C(C=C3)F)=N1)C4=CC=C(C(OCC)=O)C=C4
InChI InChI=1S/C27H25FN4O4S/c1-3-35-25(34)20-7-11-23(12-8-20)32-16-21(13-19-14-29-26(30-15-19)36-4-2)24(33)31-27(32)37-17-18-5-9-22(28)10-6-18/h5-12,14-16H,3-4,13,17H2,1-2H3

Related Products

Other Form Products of GW-1100

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
AMG 837 (calcium hydrate) 1259389-38-2 C26H22F3O4- 9
AMG 837 (sodium salt) 865231-45-4 C26H20F3NaO3 6
GPR40 Activator 1 1309435-60-6 C31H31NO3S 6
AMG 837 865231-46-5 C26H21F3O3 12
TUG-770 1402601-82-4 C19H14FNO2 13
GW9508 885101-89-3 C22H21NO3 22
TAK-875 1000413-72-8 C29H32O7S 16
GPR40 Activator 2 1312787-30-6 C28H29NO6S2 6
DC260126 346692-04-4 C32H31N5O 7
M-I C19H22O5S 0
T-1676427 1000414-39-0 C29H32O8S 0
JTT-851 C23H28O3 0
Astellas C27H30N4O4 0
MK-2305 905723-46-8 C19H13ClF3NO4S 0
Mochida 1469495-84-8 C30H35NO6S 0
BMS-986118 1610562-74-7 C25H28ClF3N4O4 2
AM-6226 C32H36F2O4 0
GPR40 agonist 1 1312788-44-5 C24H20O3 0
GPR40 agonist 2 C25H22O3 0
GPR40 agonist 3 C23H18O3 0

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Chemical and Physical Properties

Appearance:White to off-white solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:Soluble in DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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