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TAK-700 (salt)

(CAS: 426219-53-6)

Suppliers of TAK-700 (salt)

Company Name Email Tel Country
AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD304/5mg () USD464/10mg ()

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Background Information of TAK-700 (salt)

TAK-700 is an oral, selective, non-steroidal androgen synthesis inhibitor of the 17,20 lyase, which is a key enzyme in the production of steroidal hormones. IC50 value: Target: 17,20 lyase In preclinical studies, TAK-700 has been shown to bind to and inhibit the enzyme 17,20 lygase in both the testes and adrenal glands.

Solubility of TAK-700 (salt)

Solubility Sources

Storage Condition of TAK-700 (salt)

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
TAK-700 (salt) SWOG Metastatic prostate cancer 2013/3/31 2020/7/01 Phase 3 Clinical
TAK-700 (salt) Radiation Therapy Oncology Group Hormone dependent prostate cancer 2012/5/31 2014/10/01 Phase 3 Clinical
TAK-700 (salt) Millennium Pharmaceuticals Inc Hormone refractory prostate cancer 2010/10/31 2013/6/30 Phase 3 Clinical
TAK-700 (salt) Schweizerische Arbeitsgruppe fuer angewandte Krebsforschung; Swiss Group for Clinical Cancer Research Hormone refractory prostate cancer 2012/9/30 2020/12/31 Phase 3 Clinical
TAK-700 (salt) Millennium Pharmaceuticals Inc; PPD Development (S) Pte Ltd; Takeda Bio Development Center Ltd Hormone refractory prostate cancer 2010/11/30 2013/7/31 Phase 3 Clinical
TAK-700 (salt) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
532.54 C28H28N4O7 426219-53-6 TAK 700 (salt); TAK700 (salt); 6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide (2S,3S)-2,3-dihydroxy-4-oxo-4-(phenylamino)butanoate

Structure Information of TAK-700 (salt)

Smiles O=C([[email protected]]([[email protected]@H](C(NC1=CC=CC=C1)=O)O)O)O.O=C(NC)C2=CC=C3C=C(C=CC3=C2)C4(CCN5C=NC=C54)O
InChI InChI=1S/C18H17N3O2.C10H11NO5/c1-19-17(22)14-3-2-13-9-15(5-4-12(13)8-14)18(23)6-7-21-11-20-10-16(18)21;12-7(8(13)10(15)16)9(14)11-6-4-2-1-3-5-6/h2-5,8-11,23H,6-7H2,1H3,(H,19,22);1-5,7-8,12-13H,(H,11,14)(H,15,16)/t;7-,8-/m.0/s1

Related Products

Other Form Products of TAK-700 (salt)

Name CAS Formula Suppliers
TAK-700 (R-form) 752243-39-3 C18H17N3O2 2
Orteronel (racemate) 426219-18-3 C18H17N3O2 11

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Recommended Products in the Same Indication

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Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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