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Orteronel (racemate)

(CAS: 426219-18-3)

Suppliers of Orteronel (racemate)

Company Name Email Tel Country
BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD147/5mg (In stock) USD330/10mM/1mLIn DMSO (In stock) USD997/50mg (In stock)
Quality Control & MSDS Files: HPLC HNMR HPLC HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD110/5mg () USD165/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD71/2mg () USD96/5mg () USD168/10mg () USD318/25mg () USD568/50mg ()

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Background Information of Orteronel (racemate)

Orteronel racemate is a highly selective 17,20-lyase inhibitor with IC50 of 38 and 54 nM for human and rat 17, 20-Lyase, respectively. Orteronel racemate shows less active than Orteronel (IC50, 19 and 48 nM for human and rat 17, 20-Lyase, respectively).

Solubility of Orteronel (racemate)

Solubility Sources
(25°C) * In vitro DMSO 61 mg/mL (198.47 mM); Ethanol8 mg/mL (26.02 mM); Water<1 mg/mL (<1 mM); In vivo 0.5% methylcellulose30 mg/mL Selleck Chemicals LLC

Storage Condition of Orteronel (racemate)

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HPLC] [HNMR] Selleck Chemicals LLC

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Orteronel (racemate) SWOG Metastatic prostate cancer 2013/3/31 2020/7/01 Phase 3 Clinical
Orteronel (racemate) Schweizerische Arbeitsgruppe fuer angewandte Krebsforschung; Swiss Group for Clinical Cancer Research Hormone refractory prostate cancer 2012/9/30 2020/12/31 Phase 3 Clinical
Orteronel (racemate) Radiation Therapy Oncology Group Hormone dependent prostate cancer 2012/5/31 2014/10/01 Phase 3 Clinical
Orteronel (racemate) Millennium Pharmaceuticals Inc; PPD Development (S) Pte Ltd; Takeda Bio Development Center Ltd Hormone refractory prostate cancer 2010/11/30 2013/7/31 Phase 3 Clinical
Orteronel (racemate) Millennium Pharmaceuticals Inc Hormone refractory prostate cancer 2010/10/31 2013/6/30 Phase 3 Clinical
Orteronel (racemate) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
307.3465 C18H17N3O2 426219-18-3 TAK 700 racemate

Structure Information of Orteronel (racemate)

Smiles O=C(C1=CC=C2C=C(C3(O)CCN4C=NC=C43)C=CC2=C1)NC
InChI InChI=1S/C18H17N3O2/c1-19-17(22)14-3-2-13-9-15(5-4-12(13)8-14)18(23)6-7-21-11-20-10-16(18)21/h2-5,8-11,23H,6-7H2,1H3,(H,19,22)

Related Products

Other Form Products of Orteronel (racemate)

Name CAS Formula Suppliers
TAK-700 (R-form) 752243-39-3 C18H17N3O2 1
TAK-700 (salt) 426219-53-6 C28H28N4O7 2

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Recommended Products in the Same Indication

Name CAS Formula Suppliers
TAK-700 (R-form) 752243-39-3 C18H17N3O2 1
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Tasquinimod 254964-60-8 C20H17F3N2O4 9
TAK-700 (salt) 426219-53-6 C28H28N4O7 2
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Cabozantinib 849217-68-1 C28H24FN3O5 18
Odanacatib 603139-19-1 C25H27F4N3O3S 12

Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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