• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

Bexarotene

(CAS: 153559-49-0)

Suppliers of Bexarotene

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand:

Price and Availability: USD9/1mg ()

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Affix Scientific [email protected] +1-510-936-6647 USA

Fax: Purity: >98% Brand:

Price and Availability: USD600/1g (In stock)
Quality Control & MSDS Files: CoA MSDS

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

Fax: 408-493-1801Purity: Brand:

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD72/50mg () USD108/100mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

LC Laboratoies [email protected] +1-781-937-0777 +1-800-937-3720 in US and Canada only USA

Fax: +1-781-938-5420Purity: Brand:

Price and Availability: USD57/100mg (In stock) USD72/300mg (In stock) USD98/500mg (In stock) USD147/1g (In stock) USD283/2g (In stock) USD655/5g (In stock) USD994/10g (In stock)

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD72/50mg () USD108/100mg ()

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HNMR HPLC HPLC HPLC HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD72/50mg () USD108/100mg ()

Shanghai Taiheng Industry Co., Ltd. [email protected] +86 (21) 6469-9426 China

Fax: +86 (21) 6469-9429Purity: Brand:

Shanghai Yingxuan Chempharm Co., Ltd. [email protected],[email protected] +86 (21) 5199-1287 China

Fax: Purity: Brand:

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD28/10mg () USD93/100mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

Wuhan Sunrise Technology Development Company Limited [email protected],[email protected] +86 (27) 8331-4682 / +86 13554138826 China

Fax: +86 (27) 8331-4682Purity: Brand:

Wuxi Mizat Chemicals Technology Co., Ltd. [email protected],[email protected] +86 (510) 8610-6900 China

Fax: +86 (510) 8166-7021Purity: Brand:

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of Bexarotene

Bexarotene (Targretin) is a selective RXR agonist approved for the treatment of CTCL. IC50 value: Target: retinoid X receptor Exposure of NSCLC cell lines to bexarotene as a single agent had modest growth inhibitory effects (at > 1 μM).

Solubility of Bexarotene

Solubility Sources
Soluble in DMSO at 65 mg/mL; soluble in ethanol at 10 mg/mL with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-50 μM; buffers, serum, or other additives may increase or decrease the aqueous solubility. LC Laboratoies
(25°C) * In vitro DMSO 8 mg/mL (22.98 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of Bexarotene

Storage Condition Sources
Up to one week at 4°C or six months at -20°C. Affix Scientific
Store at or below -20 oC. LC Laboratoies

MSDS Information

MSDS Sources
Affix Scientific

Quality Control and Spectral Data

QC Reports Sources
[CoA] Affix Scientific
[HNMR] [HPLC] Selleck Chemicals LLC

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Bexarotene Eisai Inc Cutaneous T-cell lymphoma 2009/12/31 2013/11/30 Phase 4 Clinical
Bexarotene European Organization for Research and Treatment of Cancer Mycosis fungoides 2003/1/31 2011/6/30 Phase 3 Clinical
Bexarotene Millennium Pharmaceuticals Inc Cutaneous T-cell lymphoma 2012/8/31 2015/6/30 Phase 3 Clinical
Bexarotene Beersheva Mental Health Center Schizophrenia 2007/9/24 Phase 3 Clinical
Bexarotene Eisai Inc Metastatic non small cell lung cancer 2002/5/31 2005/3/31 Phase 3 Clinical
Bexarotene - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
348.48 C24H28O2 153559-49-0 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid; Targretin; 4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid

Structure Information of Bexarotene

Smiles CC1(C)C2=CC(C(C3=CC=C(C(O)=O)C=C3)=C)=C(C)C=C2C(C)(C)CC1
InChI InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)

Related Products

Other Form Products of Bexarotene

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
AGN 205728 859498-05-8 C29H27NO3 7
AGN 196996 958295-17-5 C24H20BrNO5 8
AGN 194310 229961-45-9 C28H24O2S 7
Acitretin (sodium) 925701-88-8 C21H25NaO3 5
Acitretin 55079-83-9 C21H26O3 22
Adapalene (sodium salt) 911110-93-5 C28H27NaO3 5
Adapalene 106685-40-9 C28H28O3 28
TTNPB 71441-28-6 C24H28O2 22
Magnolol 528-43-8 C18H18O2 35
Tazarotene 118292-40-3 C21H21NO2S 22
Fenretinide 65646-68-6 C26H33NO2 23
LG 100268 153559-76-3 C24H29NO2 7
Isotretinoin 4759-48-2 C20H28O2 31
Palovarotene 410528-02-8 C27H30N2O2 10
Retinoic acid 302-79-4 C20H28O2 34
AM580 102121-60-8 C22H25NO3 13
(R)-Flurbiprofen 51543-40-9 C15H13FO2 19
Tamibarotene 94497-51-5 C22H25NO3 17
AGN 195183 367273-07-2 C22H22ClF2NO4 8
AR7 80306-38-3 C15H12ClNO 8

Recommended Products in the Same Indication

Name CAS Formula Suppliers
LDK378 1032900-25-6 C28H36ClN5O3S 19
Pemetrexed (disodium) 150399-23-8 C20H19N5Na2O6 22
Rifabutin 72559-06-9 C46H62N4O11 20
Volasertib 755038-65-4 C34H50N8O3 17
ALK inhibitor 1 761436-81-1 C23H28BrN7O3S 8
Olaparib 763113-22-0 C24H23FN4O3 20
Afatinib (dimaleate) 850140-73-7 C32H33ClFN5O11 16
Asenapine (maleate) 85650-56-2 C21H20ClNO5 18
MGCD-265 analog 875337-44-3 C26H20FN5O2S2 14
Cariprazine 839712-12-8 C21H32Cl2N4O 9
PF-2545920 898562-94-2 C25H20N4O 10
AT-101 90141-22-3 C30H30O8 16
Tivantinib 905854-02-6 C23H19N3O2 10
lumateperone (Tosylate) 1187020-80-9 C31H36FN3O4S 7
Lu AE58054 467459-31-0 C20H19F5N2O 8
EVP-6124 550999-75-2 C16H17ClN2OS 8
Sunitinib 557795-19-4 C22H27FN4O2 19
Asenapine 65576-45-6 C17H16ClNO 7
FK866 658084-64-1 C24H29N3O2 25
Motesanib (Diphosphate) 857876-30-3 C22H29N5O9P2 20

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:230-231°C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,8 mg/mL(22.98 mM);In vitro:Water,Insoluble;In vitro:Ethanol,Insoluble;
Density:1.042 Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy Bexarotene | Bexarotene IC50 | Bexarotene price | Bexarotene cost | Bexarotene solubility | Bexarotene purchase | Bexarotene manufacturer | Bexarotene research buy | Bexarotene order | Bexarotene MSDS | Bexarotene chemical structure | Bexarotene Storage condition | Bexarotene molecular weight | Bexarotene mw | Bexarotene datasheet | Bexarotene supplier | Bexarotene cell line | Bexarotene NMR | Bexarotene MS | Bexarotene IR | Bexarotene solubility | Bexarotene Safe information | Bexarotene Qc and Spectral Information | Bexarotene Clinical Information | Bexarotene Clinical Trial | Bexarotene Route of Synthesis | Bexarotene storage condition | Bexarotene diseases and conditions | Bexarotene flash point | Bexarotene boiling point | Bexarotene melting point | Bexarotene storage condition | Bexarotene brand