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Linezolid

(CAS: 165800-03-3)

Suppliers of Linezolid

Company Name Email Tel Country
Airsea(Taizhou) Pharmaceutical Co., Ltd [email protected] +86-576-8057622, 8698002 CHINA

Fax: +86-576-8057633, 8698003Purity: Brand:

Anhui Lianchuang Pharmaceutical Chemistry Co., Ltd. [email protected],[email protected] +86 (551) 6859-6228 / 6877-9238 China

Fax: +86 (551) 6859-6338Purity: Brand:

Chengdu Sino-Strong Pharmaceutical Co., Ltd. [email protected],[email protected] +86 (28) 8278-3659 China

Fax: +86 (28) 8266-6753Purity: Brand:

Huangyan Dongsheng Pharmaceutical Chemical Co., Ltd. [email protected],[email protected] +86 (576) 8429-2571 / 8429-2561 China

Fax: +86 (576) 8429-2560Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD97/10mg (In stock) USD130/10mM/1mLIn DMSO (In stock) USD570/100mg (In stock)
Quality Control & MSDS Files: HPLC HPLC HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: >98% Brand:

Price and Availability: USD33/10mg (In stock) USD275/100mg (In stock) USD825/500mg (In stock)

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .99 Brand: TargetMol

Price and Availability: USD20/2mg () USD65/10mg () USD119/50mg () USD198/100mg ()

Tocris Bioscience Inc. [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: #99 % Brand: Tocris

Yitai Pharmatech Co., Ltd. [email protected] +86 (10) 6780-6114 / +86 13811836936 China

Fax: +86 (10) 6780-6115Purity: Brand:

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Background Information of Linezolid

Linezolid(Zyvoxid) is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics.

Solubility of Linezolid

Solubility Sources
(25°C) * In vitro DMSO 67 mg/mL (198.6 mM); Ethanol8 mg/mL (23.71 mM); Water<1 mg/mL (<1 mM); In vivo 30% PEG400+0.5% Tween80+5% Propylene glycol30 mg/mL Selleck Chemicals LLC
Soluble to 100 mM in DMSO and to 25 mM in ethanol Tocris Bioscience Inc.

Storage Condition of Linezolid

Storage Condition Sources
Store at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Anti-infection
Target Bacterial
Research Area Infection
Indications Pneumonia Nephrotoxicity Bacterial pneumonia Gram positive bacterium infection MRSA infection

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Linezolid University of Ghent Pneumonia 2013/2/28 2014/3/31 Phase 4 Clinical
Linezolid Henry Ford Health System Nephrotoxicity 2011/10/31 Phase 4 Clinical
Linezolid Cerexa Inc Bacterial pneumonia 2012/10/31 2014/10/31 Phase 4 Clinical
Linezolid Pfizer Inc Gram positive bacterium infection 2004/2/29 2005/3/31 Phase 4 Clinical
Linezolid Pfizer Inc MRSA infection 2008/11/30 2013/6/30 Phase 4 Clinical
Linezolid Pfizer Inc Pneumonia 2008/11/30 2013/6/30 Phase 4 Clinical
Linezolid - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
337.35 C16H20FN3O4 165800-03-3 (S)-N-[[3-(3-Fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide; (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

Structure Information of Linezolid

Smiles O=C(O1)N(C[[email protected]@H]1CNC(C)=O)C2=CC=C(N3CCOCC3)C(F)=C2
InChI InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

Related Products

Other Form Products of Linezolid

Name CAS Formula Suppliers
Linezolid (D3) 1127120-38-0 C16H17D3FN3O4 1

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Name CAS Formula Suppliers
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Heparin 9005-49-6 C26H42N2O37S5 6

Chemical and Physical Properties

Appearance:White to off-white solid Melting point:176-1780C
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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