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Tasquinimod

(CAS: 254964-60-8)

Suppliers of Tasquinimod

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand:

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 0.98 Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD120/5mg () USD190/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD120/5mg () USD190/10mg ()
Quality Control & MSDS Files: HNMR HNMR NP-HPLC HNMR LCMS LCMS NP-HPLC NP-HPLC MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD120/5mg () USD190/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD134/5mg ()

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Background Information of Tasquinimod

Tasquinimod(ABR-215050) is a quinoline-3-carboxamide linomide analogue with antiangiogenic and potential antineoplastic activities.

Solubility of Tasquinimod

Solubility Sources
Soluble in DMSO > 10 mM Apexbio Technology LLC
DMSO MedChemexpress Co., Ltd.

Storage Condition of Tasquinimod

Storage Condition Sources
Store at -20°C Apexbio Technology LLC

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [NP-HPLC] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage Epigenetics
Target HDAC
Research Area Cancer
Indications Hormone refractory prostate cancer Metastatic prostate cancer Prostate tumor

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Tasquinimod Active Biotech AB Hormone refractory prostate cancer 2011/3/31 2016/1/31 Phase 3 Clinical
Tasquinimod Ipsen Hormone refractory prostate cancer 2013/1/31 2016/2/29 Phase 2 Clinical
Tasquinimod Ipsen Metastatic prostate cancer 2013/1/31 2016/2/29 Phase 2 Clinical
Tasquinimod Active Biotech AB Hormone refractory prostate cancer 2007/8/10 2012/7/31 Phase 2 Clinical
Tasquinimod Duke University Hormone refractory prostate cancer 2012/1/31 2015/3/31 Phase 1 Clinical
Tasquinimod Active Biotech Research AB Prostate tumor 2009/1/31 2009/3/31 Phase 1 Clinical
Tasquinimod - Phase 3

Chemical Information

M.Wt Formula CAS No. Synonyms
406.36 C20H17F3N2O4 254964-60-8 ABR-215050;ABR215050;ABR 215050; 4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)phenyl)-1,2-dihydroquinoline-3-carboxamide

Structure Information of Tasquinimod

Smiles O=C(C1=C(O)C2=C(N(C)C1=O)C=CC=C2OC)N(C)C3=CC=C(C(F)(F)F)C=C3
InChI InChI=1S/C20H17F3N2O4/c1-24(12-9-7-11(8-10-12)20(21,22)23)18(27)16-17(26)15-13(25(2)19(16)28)5-4-6-14(15)29-3/h4-10,26H,1-3H3

Related Products

Other Form Products of Tasquinimod

Name CAS Formula Suppliers

Recommended Products in Same Target

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Recommended Products in the Same Indication

Name CAS Formula Suppliers
TAK-700 (R-form) 752243-39-3 C18H17N3O2 2
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KX2-391 897016-82-9 C26H29N3O3 14
AT-101 90141-22-3 C30H30O8 16
Bicalutamide 90357-06-5 C18H14F4N2O4S 30
Enzalutamide 915087-33-1 C21H16F4N4O2S 21
Tivozanib 475108-18-0 C22H19ClN4O5 22
Orteronel 566939-85-3 C18H17N3O2 9
Linsitinib 867160-71-2 C26H23N5O 18
Fenretinide 65646-68-6 C26H33NO2 23
Leuprolide (Acetate) 74381-53-6 C61H88N16O14 21
Retaspimycin 857402-23-4 C31H45N3O8 9
Retaspimycin (Hydrochloride) 857402-63-2 C31H46ClN3O8 10
Bafetinib 859212-16-1 C30H31F3N8O 22
AT13387 912999-49-6 C24H31N3O3 19
Ganetespib 888216-25-9 C20H20N4O3 17
Orteronel (racemate) 426219-18-3 C18H17N3O2 11
TAK-700 (salt) 426219-53-6 C28H28N4O7 4
TOK-001 851983-85-2 C26H32N2O 18
RO4929097 847925-91-1 C22H20F5N3O3 16

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,81 mg/mL(199.33 mM);In vitro:Ethanol,11 mg/mLwarmed(27.06 mM);In vitro:Water,Insoluble;In vivo:Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):5% DMSO+30% PEG 300+ddH2OFor best results,
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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