• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

Betulinic acid

(CAS: 472-15-1)

Suppliers of Betulinic acid

Company Name Email Tel Country
AA Blocks LLC [email protected] +1 858-523-8231

Fax: Purity: Brand:

AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand:

AbMole BioScience [email protected] 1-800-660-8580 USA

Fax: Purity: Brand:

Adipogen Corporation [email protected] (858) 457-8383 USA

Fax: (858) 457-8484Purity: Brand:

Adipogen Corporation [email protected] (858) 457-8383 USA

Fax: (858) 457-8484Purity: Brand:

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Affix Scientific [email protected] +1-510-936-6647 USA

Fax: Purity: ≥98% Brand:

Price and Availability: USD450/500mg (In stock) USD600/1g (In stock)
Quality Control & MSDS Files: CoA MSDS

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

Astatech, Inc. [email protected] +1 (215) 785-3197 USA

Fax: +1 (215) 785-2656Purity: Brand:

BLD Pharmatech [email protected] +86-21-61629022

Fax: Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 0.98 Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

Fax: 408-493-1801Purity: Brand:

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

Boehringer Ingelheim GmbH [email protected] +49 6132-770 Germany

Fax: +49 6132-720Purity: Brand:

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD64/100mg () USD102/200mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Extrasynthese Chemical S.A.S. [email protected] +33 (47) 898-2034 France

Fax: +33 (47) 898-1945Purity: Brand:

Hangzhou Skyherb Technologies Co., Ltd. [email protected] +86 (571) 8805-3319 China

Fax: +86 (571) 8805-4060Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD64/100mg () USD102/200mg ()
Quality Control & MSDS Files: HNMR MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Phytomarker Ltd. [email protected] +86 (22) 2635-8246 China

Fax: Purity: Brand:

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD50/10mg (In stock) USD90/25mg (In stock) USD150/50mg (In stock) USD210/100mg (In stock)
Quality Control & MSDS Files: HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD64/100mg () USD102/200mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD43/10mg () USD77/25mg () USD133/50mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

Wilshire Technologies [email protected] +1 (609) 683-1117 USA

Fax: Purity: Brand:

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of Betulinic acid

Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells, also is a inhibitor of HIV-1 with EC50 of 1.4 μ M. IC50 Value: 1.4 μM (EC50, HIV1) Target: Apoptosis inducer; Topoisomerase in vitro: Betulinic acid shows anti-HIV activity by blocking HIV replication in H9 lymphocytes with an EC50 value of 1.4 μM and inhibiting uninfected H9 cell growth with an IC50 value of 13 μM.

Solubility of Betulinic acid

Solubility Sources
DMSO 50 mg/ml MedChemexpress Co., Ltd.
DMSO mg/mL (<1 mM) ; Water mg/mL (<1 mM) ; Ethanol mg/mL (<1 mM) Selleck Chemicals LLC
Soluble to 50 mM in DMSO Tocris Bioscience Inc.

Storage Condition of Betulinic acid

Storage Condition Sources
Up to one week at 4°C or six months at -20°C. Affix Scientific
Store at +4°C Tocris Bioscience Inc.

MSDS Information

MSDS Sources
Affix Scientific
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[CoA] Affix Scientific
[HNMR] MedChemexpress Co., Ltd.
[HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage Autophagy Apoptosis
Target Apoptosis Topoisomerase Autophagy
Research Area Cancer
Indications Dysplastic nevus syndrome Melanoma

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Betulinic acid University of Illinois Dysplastic nevus syndrome 2006/1/31 Phase 2 Clinical
Betulinic acid Advanced Life Science Institute Inc Melanoma 2008/6/30 Phase 1 Clinical
Betulinic acid - Suspended
Betulinic acid - Phase 2

Chemical Information

M.Wt Formula CAS No. Synonyms
456.7 C30H48O3 472-15-1 3beta-Hydroxy-20(29)-lupaene-28-oic acid; (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylic acid

Structure Information of Betulinic acid

Smiles OC([[email protected]@]1(CC2)[[email protected]@]([[email protected]]3([H])[[email protected]]2(C)[[email protected]@](CC[[email protected]]4([H])[[email protected]]5(C)CC[[email protected]](O)C4(C)C)(C)[[email protected]]5([H])CC3)([[email protected]](C(C)=C)CC1)[H])=O
InChI InChI=1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1

Related Products

Other Form Products of Betulinic acid

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
Epibrassinolide 78821-43-9 C28H48O6 10
Columbianadin 5058-13-9 C19H20O5 10
NSC348884 81624-55-7 C38H40N10 15
SMIP004 143360-00-3 C13H19NO 11
Meisoindigo 97207-47-1 C17H12N2O2 16
Betulin 473-98-3 C30H50O2 26
Costunolide 553-21-9 C15H20O2 17
Baohuoside I 113558-15-9 C27H30O10 11
Bisdemethoxycucurmin 24939-16-0 C19H16O4 6
Demethoxycurcumin 22608-11-3 C20H18O5 8
Cisplatin 15663-27-1 Cl2H6N2Pt 32
(E)-[6]-Dehydroparadol 878006-06-5 C17H24O3 3
PM00104 308359-57-1 C37H38F3N3O8 5
Episilvestrol 697235-39-5 C34H38O13 6
Trabectedin 114899-77-3 C39H43N3O11S 13
Myricetin 529-44-2 C15H10O8 22
Adarotene 496868-77-0 C25H26O3 11
(±)-[6]-Gingerol 39886-76-5 C17H26O4 8
Silvestrol aglycone 960365-65-5 C27H26O8 6
Elesclomol 488832-69-5 C19H20N4O2S2 15

Recommended Products in the Same Indication

Name CAS Formula Suppliers
Trametinib 871700-17-3 C26H23FIN5O4 21
MLN4924 905579-51-3 C21H25N5O4S 16
SB-590885 405554-55-4 C27H27N5O2 18
Fenretinide 65646-68-6 C26H33NO2 23
FK866 658084-64-1 C24H29N3O2 25
Retaspimycin 857402-23-4 C31H45N3O8 9
Retaspimycin (Hydrochloride) 857402-63-2 C31H46ClN3O8 10
Temozolomide 85622-93-1 C6H6N6O2 34
Dinaciclib 779353-01-4 C21H28N6O2 17
Elesclomol 488832-69-5 C19H20N4O2S2 15
AS703026 1236699-92-5 C15H15FIN3O3 18
Trametinib (DMSO solvate) 1187431-43-1 C28H29FIN5O5S 10
LY3009120 1454682-72-4 C23H29FN6O 15
Dabrafenib 1195765-45-7 C23H20F3N5O2S2 19
LEE011 (succinate) 1374639-75-4 C27H36N8O5 9
LEE011 (succinate hydrate) 1374639-79-8 C27H38N8O6X 8
Dabrafenib (Mesylate) 1195768-06-9 C24H24F3N5O5S3 14
LEE011 1211441-98-3 C23H30N8O 21
LEE011 (hydrochloride) 1211443-80-9 C23H31ClN8O 8
MLN4924 (hydrochloride) 1160295-21-5 C21H26ClN5O4S 9

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:295-298 °C (dec.)(lit.)
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,20 mg/mL(43.79 mM);In vitro:Ethanol,10 mg/mL(21.89 mM);In vitro:Water,Insoluble;
Density: Merck:1190
BRN: Refractive Index: 7.8 ° (C=0.9, Pyridine)
Vapour: EINECS:207-448-8
Optical Rotation: alpha:

Tags: buy Betulinic acid | Betulinic acid IC50 | Betulinic acid price | Betulinic acid cost | Betulinic acid solubility | Betulinic acid purchase | Betulinic acid manufacturer | Betulinic acid research buy | Betulinic acid order | Betulinic acid MSDS | Betulinic acid chemical structure | Betulinic acid Storage condition | Betulinic acid molecular weight | Betulinic acid mw | Betulinic acid datasheet | Betulinic acid supplier | Betulinic acid cell line | Betulinic acid NMR | Betulinic acid MS | Betulinic acid IR | Betulinic acid solubility | Betulinic acid Safe information | Betulinic acid Qc and Spectral Information | Betulinic acid Clinical Information | Betulinic acid Clinical Trial | Betulinic acid Route of Synthesis | Betulinic acid storage condition | Betulinic acid diseases and conditions | Betulinic acid flash point | Betulinic acid boiling point | Betulinic acid melting point | Betulinic acid storage condition | Betulinic acid brand