Retinoic acid
(CAS: 302-79-4)
Suppliers of Retinoic acid
Background Information of Retinoic acid
All-trans retinoic acid (ATRA; Vitamin A acid) has been widely investigated for treatments of many cancers including prostate cancer.
IC50 Value:
Target: RAR
in vitro: ATRA was able to induce the growth arrest and to increase HOXB13 expression in AR?prostate cancer cells.
Solubility of Retinoic acid
Storage Condition of Retinoic acid
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Quality Control and Spectral Data
Mechanism and Indications
Clinical Information
Product Name |
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Indications |
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End Date |
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Retinoic acid
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Launched |
Chemical Information
M.Wt |
Formula |
CAS No. |
Synonyms |
300.44 |
C20H28O2 |
302-79-4 |
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid; all-trans-Retinoic acid; Vitamin A acid; (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid |
Structure Information of Retinoic acid
Smiles |
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1 |
InChI |
InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+ |
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Safety Data of Retinoic acid
Chemical and Physical Properties
Appearance:Light yellow to yellow solid |
Melting point:180-181 °C(lit.) |
Boiling point: |
Flash Point: |
Water Solubility: insoluble |
Solubility:In vitro:DMSO,60 mg/mL(199.73 mM);In vitro:Ethanol,6 mg/mL(19.97 mM);In vitro:Water, Insoluble; |
Density: |
Merck:14,8165 |
BRN:2057223 |
Refractive Index: |
Vapour: |
EINECS:206-129-0 |
Optical Rotation: |
alpha: |