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Sulfasalazine

(CAS: 599-79-1)

Suppliers of Sulfasalazine

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

Fax: Purity: Brand:

American Custom Chemicals Corp. [email protected] +1 (858) 201-6118 USA

Fax: +1 (858) 451-8607Purity: Brand:

Anhui Jixi Huihuang Chemical Co., Ltd. [email protected] +86 (563) 815-6339 / 815-2476 China

Fax: +86 (563) 816-1780Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD60/1g () USD96/5g ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/1g () USD96/5g ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Pure Chemistry Scientific Inc. [email protected] 857-928-2050 / 857-366-6788 USA

Fax: 617-206-9595Purity: >98% Brand:

Price and Availability: USD30/1g (In stock)

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HPLC HNMR HPLC HPLC HPLC HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD60/1g () USD96/5g ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD56/10mg () USD102/50mg () USD153/200mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: #98 % Brand: Tocris

Xinzhen Zhendong Chemical Plant [email protected] +86 (512) 5766-6922 China

Fax: +86 (512) 5766-6290Purity: Brand:

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Background Information of Sulfasalazine

Sulfasalazine, a sulfa agent and a derivative of mesalazine, is used primarily as an anti-inflammatory agent. Target: Others Sulfasalazine (Azulfidine), used to treat pain and swelling in arthritis, belongs to a class of drugs called sulfa drugs.

Solubility of Sulfasalazine

Solubility Sources
DMSO 80 mg/mL; Water <1 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 80 mg/mL (200.8 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) Selleck Chemicals LLC
Soluble to 100 mM in DMSO Tocris Bioscience Inc.

Storage Condition of Sulfasalazine

Storage Condition Sources
Store at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HPLC] [HNMR] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways NF-κB Autophagy
Target Autophagy NF-κB
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Sulfasalazine - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
398.39 C18H14N4O5S 599-79-1 2-Hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]benzoic acid; 5-(p-(2-pyridylsulfamoyl)phenylazo)salicylic acid; Salazosulfapyridine; Sulfasalazine; (E)-2-hydroxy-5-((4-(N-(pyridin-2-yl)sulfamoyl)phenyl)diazenyl)benzoic acid

Structure Information of Sulfasalazine

Smiles O=S(C1=CC=C(/N=N/C2=CC=C(O)C(C(O)=O)=C2)C=C1)(NC3=CC=CC=N3)=O
InChI InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)/b21-20+

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Safety Data of Sulfasalazine

Hazard Symbols:Xn Risk Statements:42/43 Safety Statements:22-29/56-45
Transport Information: HS Code: RTECS:VO6250000
WGK Germany:2

Chemical and Physical Properties

Appearance:light yellow to khaki Solid Melting point:260-265 °C (dec.)(lit.)
Boiling point: Flash Point:
Water Solubility: <0.1 g/100 mL at 25 ºC Solubility:In vitro:DMSO,80 mg/mL(200.8 mM);In vitro:Water,Insoluble;In vitro:Ethanol,Insoluble;
Density: Merck:8942
BRN: Refractive Index:
Vapour: EINECS:209-974-3
Optical Rotation: alpha:

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