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Talarozole (R enantiomer)

(CAS: 870093-23-5)

Suppliers of Talarozole (R enantiomer)

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD228/1mg () USD468/5mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD228/1mg () USD468/5mg ()

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD228/1mg () USD468/5mg ()

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Background Information of Talarozole (R enantiomer)

Talarozole, also known as R115866, is a CYP26 inhibitor under development for the treatment of acne, psoriasis and other keratinization disorders. Talarozole inhibits the metabolism of retinoic acid by blocking the cytochrome P450 enzyme isoform CYP26, a retinoic acid hydroxylase. Because of this mechanism, it is called a retinoic acid metabolism blocking agent (RAMBA).

Solubility of Talarozole (R enantiomer)

Solubility Sources
DMSO: ≥ 51 mg/mL CHEMSCENE, LLC
DMSO: ≥ 51 mg/mL MedChemexpress Co., Ltd.

Storage Condition of Talarozole (R enantiomer)

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease
Target Cytochrome P450
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Talarozole (R enantiomer) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
377.5058 C21H23N5S 870093-23-5 (R)-Talarozole

Structure Information of Talarozole (R enantiomer)

Smiles CCC(CC)[[email protected]](C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4N=CN=C4
InChI InChI=1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25)/t20-/m1/s1

Related Products

Other Form Products of Talarozole (R enantiomer)

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Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:Soluble in DMSO, not in water
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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