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Homoharringtonine

(CAS: 26833-87-4)

Suppliers of Homoharringtonine

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Ankang Zhongke Maidisen Natural Pharmaceutical Co., Ltd. [email protected] +86 (29) 8223-6926 China

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD102/10mg () USD348/50mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Conier Chem & Pharma Co., Ltd. [email protected],[email protected] +86 (23) 6292-2305 China

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Hangzhou Bm Chemical Co., Ltd. [email protected] +86 (571) 8733-0289 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD102/10mg () USD348/50mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Shaanxi Sciphar Biotechnology Co., Ltd. [email protected] +86 (29) 8835-3228 / 8838-9752 / 8300-6195 China

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD102/10mg () USD348/50mg ()

Sino-Future Bio-Tech Co., Ltd. [email protected] +86 (29) 8318-2005 China

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Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: #99 % Brand: Tocris

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Background Information of Homoharringtonine

Homoharringtonine(HHT) is a cytotoxic alkaloid from the evergreen tree. Target: Others Homoharringtonine (HHT) is a cephalotaxine alkaloid with reported efficacy in acute myelogenous leukemia (AML).

Solubility of Homoharringtonine

Solubility Sources
DMSO MedChemexpress Co., Ltd.
Soluble to 100 mM in DMSO and to 50 mM in ethanol Tocris Bioscience Inc.

Storage Condition of Homoharringtonine

Storage Condition Sources
Store at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways JAK/STAT Signaling Stem Cell/Wnt
Target STAT
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Homoharringtonine - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
545.62 C29H39NO9 26833-87-4 Omacetaxine mepesuccinate;HHT; (R)-1-((11bS,12S,14aR)-13-methoxy-2,3,5,6,11b,12-hexahydro-1H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-12-yl) 4-methyl 2-hydroxy-2-(4-hydroxy-4-methylpentyl)succinate

Structure Information of Homoharringtonine

Smiles [H][[email protected]@]12[[email protected]](CCC3)(C=C(OC)[[email protected]]2(OC([[email protected]](CCCC(O)(C)C)(O)CC(OC)=O)=O)[H])N3CCC4=CC5=C(OCO5)C=C14
InChI InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m1/s1

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Safety Data of Homoharringtonine

Hazard Symbols:T+,Xi Risk Statements:26/27/28-36/37/38-28 Safety Statements:36/37/39-45-27-26-36/37-28
Transport Information: HS Code: RTECS:FK0260000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:144-146 C
Boiling point: Flash Point:
Water Solubility: Solubility:Soluble in DMSO > 10 mM
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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