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Isotretinoin

(CAS: 4759-48-2)

Suppliers of Isotretinoin

Company Name Email Tel Country
Abcam [email protected] (888) 77-ABCAM (22226) USA

Fax: (877) 774-8286 / (617) 577-4201Purity: Brand:

Price and Availability: USD139/50mg ()

Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 0.96 Brand: Alfa Chemistry

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD60/100mg () USD126/500mg ()

Chongqing Huapont Pharm. Co., Ltd. [email protected] +86 (23) 6788-9222 / 6788-6928 China

Fax: +86 (23) 6788-9222 / 6788-6927Purity: Brand:

Hande Industry & Trade Holdings Ltd. [email protected] +86 (755) 8386-5183 China

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Hande Pharma Limited [email protected] +86 (512) 6936-3202 China

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Hangzhou Starshine Pharmaceutical Co., Ltd. [email protected],[email protected] +86 (571) 8993-6035 China

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J&K Scientific Ltd. [email protected];[email protected] 400-666-7788 / +86 10 8284 8833 China

Fax: +86 10 8284 9933Purity: Brand:

Price and Availability: RMB923/250mg ()

Jiangxi Synergy Pharmaceuticals Co., Ltd. [email protected] +86 (795) 460-5773 / 460-5771 / 460-5608 China

Fax: +86 (795) 460-5772Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/100mg () USD126/500mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

Nexchem Pharmaceutical Co., Ltd. [email protected] +86 (579) 8220-7640 China

Fax: +86 (579) 8220-7642Purity: Brand:

Parling (Shanghai) PharmaTech Co., Ltd. [email protected],[email protected] +86 (21) 3616-2075 / +86 15901935043 China

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Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Price and Availability: USD37/100mg ()

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD97/50mg (In stock) USD120/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HNMR HPLC HPLC HNMR HPLC

Shanghai Amadis Bio-Technology Co., Ltd [email protected] (852)-2815 8172 CHINA

Fax: +86-21-36162076Purity: Brand:

Shanghai Chely Co., Ltd. [email protected] +86 (21) 6117-0103 / 6117-0105 China

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD60/100mg () USD126/500mg ()

Shanghai Longschem Co., Ltd. [email protected] +86 (21) 3635-6756 China

Fax: +86 (21) 3656-6757Purity: Brand:

Shangyu Zhebang Pharmaceutical Co., Ltd. [email protected] zbpharm.com +86 (575) 8273-2308 China

Fax: +86 (575) 8272-8901Purity: Brand:

Sigma-Aldrich, Inc. [email protected] +86 (21) 6141-5566 / 800-819-3336 USA

Fax: Purity: Brand:

Price and Availability: USD67/100mg ()

Spectrum Chemical Mfg. Corp. [email protected] +1 (310) 516-8000 USA

Fax: +1 (310) 516-7512Purity: Brand:

Price and Availability: USD267/500mg ()

Taizhou Hengfeng Pharmaceutical & Chemical Co., Ltd. [email protected] +86 (576) 8599-3534 China

Fax: +86 (576) 8599-3006Purity: Brand:

Taizhou Intouch Import & Export Trading Company [email protected] +86 (576) 8869-8596 China

Fax: +86 (576) 8889-1466Purity: Brand:

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD20/2mg () USD42/10mg () USD64/50mg () USD122/200mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

Price and Availability: USD59/50mg ()

Tokyo Chemical Industry Co., Ltd. [email protected] 03-3668-0489 Japan

Fax: 03-3668-0520Purity: Brand:

Price and Availability: USD61/100mg ()

Toronto Research Chemicals Inc. [email protected] +1 (416) 665-9696 Canada

Fax: +1 (416) 665-4439Purity: Brand:

Price and Availability: USD50/50mg ()

Zhangjiagang Sunrise Fine Chemical Co., Ltd. [email protected] +86 (574) 8797-0832 China

Fax: +86 (574) 8770-1738Purity: Brand:

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Background Information of Isotretinoin

Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne.

Solubility of Isotretinoin

Solubility Sources
DMSO 60 mg/mL; Water <1 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 60 mg/mL (199.7 mM); Ethanol1 mg/mL warming (3.32 mM); Water<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of Isotretinoin

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease
Target RAR/RXR
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Isotretinoin - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
300.44 C20H28O2 4759-48-2 13-cis-Retinoic acid; 13-cis-Vitamin A acid; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-cis-4-trans-6-trans-8-trans-nonatetraenoic acid; (2Z,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid

Structure Information of Isotretinoin

Smiles CC(/C=C/C=C(C=CC1=C(CCCC(C)1C)C)C)=C/C(O)=O
InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14-

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Other Form Products of Isotretinoin

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Acitretin (sodium) 925701-88-8 C21H25NaO3 5
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Safety Data of Isotretinoin

Hazard Symbols:T Risk Statements:R36/37/38;R61 Safety Statements:S26;S37/39;S45;S53
Transport Information: HS Code: RTECS:VH6440000
WGK Germany:3

Chemical and Physical Properties

Appearance:Off-white to orange Solid Melting point:172-175 °C(lit.)
Boiling point: Flash Point:
Water Solubility: insoluble Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:225-296-0
Optical Rotation: alpha:

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