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SB1317

(CAS: 937270-47-8)

Suppliers of SB1317

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

Fax: Purity: Brand:

Price and Availability: USD220/10mg (Out of stock)

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Price and Availability: USD90/5mg ()

Aladdin [email protected] 400 620 6333 China

Fax: 021 5102 6000Purity: Brand:

Price and Availability: RMB2024/5mg () RMB3320/10mg () RMB11858/100mg ()

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD107/5mg (Ship Within 10-14 Days)

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 0.98 Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD110/5mg () USD150/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD110/5mg () USD150/10mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Price and Availability: USD90/5mg ()
Quality Control & MSDS Files: CoA HNMR HPLC MS MSDS

Pure Chemistry Scientific Inc. [email protected] 857-928-2050 / 857-366-6788 USA

Fax: 617-206-9595Purity: 97% Brand:

Price and Availability: USD104/10mg (In stock)

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD110/5mg () USD150/10mg ()

eNovation Chemicals LLC [email protected] 908-635-2322 USA

Fax: 888-575-4219Purity: Brand:

Price and Availability: USD385/25mg ()

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Background Information of SB1317

SB1317(TG-02) is a novel small molecule potent CDK2/JAK2/FLT3 inhibitor with IC50s of 13/73/56 nM respectively. IC50 Value: 13/73/56 nM(CDK2/JAK2/FLT3) Target: CDK2/JAK2/FLT3 TG02 is a novel pyrimidine-based multi-kinase inhibitor that inhibits CDKs 1, 2, 7 and 9 together with JAK2 and FLT3.

Solubility of SB1317

Solubility Sources
Soluble in DMSO, not in water MedKoo Biosciences, Inc.

Storage Condition of SB1317

Storage Condition Sources
Storage condition:Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Stock solution storage:0 - 4 C for short term (days to weeks), or -20 C for long term (months). Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. MedKoo Biosciences, Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.
MedKoo Biosciences, Inc.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[CoA] [HNMR] [HPLC] [MS] MedKoo Biosciences, Inc.

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
SB1317 Tragara Pharmaceuticals Inc Chronic lymphocytic leukemia 2012/9/30 2014/8/31 Phase 1 Clinical
SB1317 Tragara Pharmaceuticals Inc Hematological neoplasm 2010/8/31 2013/7/31 Phase 1 Clinical
SB1317 - Phase 2

Chemical Information

M.Wt Formula CAS No. Synonyms
372.46 C23H24N4O 937270-47-8 TG02;SB 1317;TG 02;SB-1317;TG-02;

Structure Information of SB1317

Smiles CN1CC2=CC(NC3=NC(C4=CC(OCC/C=C/C1)=CC=C4)=CC=N3)=CC=C2
InChI InChI=1S/C23H24N4O/c1-27-13-3-2-4-14-28-21-10-6-8-19(16-21)22-11-12-24-23(26-22)25-20-9-5-7-18(15-20)17-27/h2-3,5-12,15-16H,4,13-14,17H2,1H3,(H,24,25,26)/b3-2+

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Other Form Products of SB1317

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Duvelisib 1201438-56-3 C22H17ClN6O 24

Chemical and Physical Properties

Appearance:White to off-white solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:>44.87mg/mL in DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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