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Proparacaine (Hydrochloride)

(CAS: 5875-06-9)

Suppliers of Proparacaine (Hydrochloride)

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AbMole BioScience [email protected] 1-800-660-8580 USA

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Abcam [email protected] (888) 77-ABCAM (22226) USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Aladdin [email protected] 400 620 6333 China

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Alfa Chemistry [email protected] 1-201-478-8534 USA

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Carbosynth Limited [email protected] +44 (1635) 578-444

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Changzhou Lanling Chemical Co., Ltd. [email protected] +86 (519) 8881-2755 China

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Hangzhou Bm Chemical Co., Ltd. [email protected] +86 (571) 8733-0289 China

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Jinan Chenghui-Shuangda Chemical Co., Ltd. [email protected] +86 (531) 5889-7070 / 5889-7066 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Quality Control & MSDS Files: HNMR LCMS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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ProbeChem [email protected] 86-21-80183644

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Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock) USD163/10mM(in 1mL DMSO) (in 1mL DMSO)
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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Spectrum Chemical Mfg. Corp. [email protected] +1 (310) 516-8000 USA

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Target Molecule Corp. [email protected] (857) 239-0968 USA

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Price and Availability: USD20/2mg () USD62/10mg () USD135/50mg () USD221/100mg ()

Tokyo Chemical Industry Co., Ltd. [email protected] 03-3668-0489 Japan

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Wonder Synthesis (Beijing) Science and Development Co., Ltd. [email protected],[email protected] +86 (10) 8482-6062 China

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Background Information of Proparacaine (Hydrochloride)

Proparacaine Hydrochloride is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM. IC50 Value: 3.4 mM(ED50) [1] Target: Sodium Channel in vitro: Proparacaine is more potent and less toxic than cocaine [1].

Solubility of Proparacaine (Hydrochloride)

Solubility Sources
DMSO 12 mg/mL; Water 65 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 12 mg/mL (36.27 mM); Water66 mg/mL (199.48 mM); Ethanol<1 mg/mL (<1 mM); In vivo Saline30 mg/mL Selleck Chemicals LLC

Storage Condition of Proparacaine (Hydrochloride)

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Membrane Transporter/Ion Channel
Target Sodium Channel
Research Area Neurological Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Proparacaine (Hydrochloride) - No Development Reported
Proparacaine (Hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
330.85 C16H27ClN2O3 5875-06-9 Proxymetacaine Hydrochloride; 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride

Structure Information of Proparacaine (Hydrochloride)

Smiles O=C(OCCN(CC)CC)C1=CC=C(OCCC)C(N)=C1.[H]Cl
InChI InChI=1S/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H

Related Products

Other Form Products of Proparacaine (Hydrochloride)

Name CAS Formula Suppliers
Proparacaine (Hydrochloride) 5875-06-9 C16H27ClN2O3 5

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Safety Data of Proparacaine (Hydrochloride)

Hazard Symbols:Xn Risk Statements:20/21/22-36-43 Safety Statements:26-36
Transport Information: HS Code: RTECS:DG3065000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:Water,66 mg/mL(199.48 mM);In vitro:DMSO,12 mg/mL(36.27 mM);In vitro:Ethanol,Insoluble;In vivo:Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):SalineFor best results, use promptly after mixing
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:227-541-7
Optical Rotation: alpha:

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