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Gossypol

(CAS: 303-45-7)

Suppliers of Gossypol

Company Name Email Tel Country
Abcam [email protected] (888) 77-ABCAM (22226) USA

Fax: (877) 774-8286 / (617) 577-4201Purity: Brand:

Price and Availability: USD55/25mg ()

Affix Scientific [email protected] +1-510-936-6647 USA

Fax: Purity: >98 % Brand:

Price and Availability: USD400/100mg (In stock) USD750/500mg (In stock)
Quality Control & MSDS Files: CoA MSDS

AvaChem Scientific LLC [email protected] +1 (210) 667-3815 USA

Fax: +1 (210) 592-6206Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

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BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

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Price and Availability: USD95/50mg ()

CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD90/100mg () USD161/200mg ()

Carbosynth Limited [email protected] +44 (1635) 578-444

Fax: +44 (1635) 579-444Purity: Brand:

Price and Availability: USD50/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Price and Availability: USD60/50mg ()

Hubie Xinyuanshun Pharm&Chem Co., Ltd. [email protected] +86 (27) 5066-4929 / +86 13971561712 China

Fax: +86 (27) 5066-4927Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD90/100mg () USD161/200mg ()

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Price and Availability: USD36/20mg ()

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD88/100mg (In stock) USD170/250mg (In stock)
Quality Control & MSDS Files: HPLC HPLC HPLC HPLC HPLC

Shaanxi Xinshenglong Pharmaceutical Co., Ltd. [email protected] +86 (29) 8730-3961 China

Fax: +86 (29) 8821-0851Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD90/100mg () USD161/200mg ()

Sigma-Aldrich, Inc. [email protected] +86 (21) 6141-5566 / 800-819-3336 USA

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Price and Availability: USD150/100mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD72/100mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

Price and Availability: USD95/50mg ()

Wuhan ChemFaces Biochemical Co., Ltd. [email protected]; [email protected] +86-27-84254680 China

Fax: +86-27-84254680Purity: Brand:

Price and Availability: USD158/20mg ()

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Background Information of Gossypol

Gossypol has been known to exert a potential for anti-cancer, anti-inflammatory and other important therapeutic activities, gossypol binds and antagonizes anti-apoptotic effect of Bcl-2 family proteins IC50 value: Target: Bcl-2; anticancer agent The substance, a yellow pigment similar to flavonoids, is present in cottonseed oil.

Solubility of Gossypol

Solubility Sources
DMSO MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 100 mg/mL (172.82 mM); Ethanol21 mg/mL (36.29 mM); Water<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of Gossypol

Storage Condition Sources
Up to one week at 4°C or six months at -20°C. Affix Scientific

MSDS Information

MSDS Sources
Affix Scientific

Quality Control and Spectral Data

QC Reports Sources
[CoA] Affix Scientific
[HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Apoptosis
Target Bcl-2 Family
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Gossypol - Discontinued
Gossypol - Phase 3

Chemical Information

M.Wt Formula CAS No. Synonyms
518.55 C30H30O8 303-45-7 2,2'-Bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene); 1,1',6,6',7,7'-hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-8,8'-dicarbaldehyde

Structure Information of Gossypol

Smiles OC1=C(C2=C(O)C(C(C=O)=C3O)=C(C(C(C)C)=C3O)C=C2C)C(C)=CC4=C1C(C=O)=C(O)C(O)=C4C(C)C
InChI InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12,33-38H,1-6H3

Related Products

Other Form Products of Gossypol

Name CAS Formula Suppliers
Gossypol (acetic acid) 12542-36-8 C32H34O10 13

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Safety Data of Gossypol

Hazard Symbols:Xn Risk Statements:R22;R40 Safety Statements:S22;S36
Transport Information: HS Code: RTECS:DU3100000
WGK Germany:3

Chemical and Physical Properties

Appearance: Melting point:181-183 C
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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