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Cisatracurium (besylate)

(CAS: 96946-42-8)

Suppliers of Cisatracurium (besylate)

Company Name Email Tel Country
Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 0.99 Brand: BOC Sciences

Price and Availability: USD169/250mg (In stock)

Beijing Eagle Sky Pharmatech Co., Ltd. [email protected],[email protected] +86 (10) 5979-9429 China

Fax: +86 (10) 5804-3698Purity: Brand:

Beijing Lang Rebone Technology Co., Ltd. [email protected] +86 (10) 5979-9429 / +86 18612220856 China

Fax: +86 (10) 8895-6459Purity: Brand:

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD397/100mg () USD1543/500mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Clearsynth Labs Limited [email protected] Worldwide Helpline No. +1-415-685-4395; US & Canada (Toll-free) : +1-800-650-8239; Europe : +44-20-3286-0885; India : +91-22-26355700 India

Fax: Purity: Brand:

Price and Availability: USD100/25mg ()

Dongying MaiDiSen Biotechnology Research Institute [email protected] +86 (546) 826-8050 / +86 15954635451 China

Fax: +86 (546) 826-8050Purity: Brand:

Lianyungang Guike Pharmaceutical Co., ltd. [email protected] +86 (518) 8607-0808 / 8607-0855 China

Fax: +86 (518) 8607-0852Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD397/100mg () USD1543/500mg ()
Quality Control & MSDS Files: HNMR LCMS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Price and Availability: USD300/100mg ()

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD110/25mg (In stock) USD140/10mM/1mLIn DMSO (In stock) USD176/10mM(in 1mL DMSO) (in 1mL DMSO) USD370/100mg (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC

Shandong Boyuan Pharmaceutical Co., Ltd. [email protected],[email protected] +86 (531) 6995-4981 / 8896-3280 China

Fax: +86 (531) 8896-4879Purity: Brand:

Shandong Kingnod Pharmaceuticals Co., Ltd. [email protected] +86 (533) 815-5527 / +86 15053385713 China

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD397/100mg () USD1543/500mg ()

Sigma-Aldrich, Inc. [email protected] +86 (21) 6141-5566 / 800-819-3336 USA

Fax: Purity: Brand:

Price and Availability: USD176/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .9 Brand: TargetMol

Price and Availability: USD43/10mg () USD74/25mg () USD133/50mg ()

Zhejiang Haisen Pharmaceutical Co., Ltd [email protected] +86-579-86773108 CHINA

Fax: +86-579-86773083Purity: Brand:

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Background Information of Cisatracurium (besylate)

Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission. Target: AChR alpha-2 Cisatracurium is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Solubility of Cisatracurium (besylate)

Solubility Sources
DMSO 250 mg/mL; Water 48 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 249 mg/mL (200.24 mM); Ethanol249 mg/mL (200.24 mM); Water47 mg/mL (37.79 mM) Selleck Chemicals LLC

Storage Condition of Cisatracurium (besylate)

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Membrane Transporter/Ion Channel Neuronal Signaling Autophagy
Target nAChR Autophagy
Research Area Neurological Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Cisatracurium (besylate) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
1243.48 C65H82N2O18S2 96946-42-8 Nimbex; (1R,1'R,2R,2'R)-2,2'-((pentane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium) benzenesulfonate

Structure Information of Cisatracurium (besylate)

Smiles O=C(OCCCCCOC(CC[[email protected]+]1(C)[[email protected]](CC2=CC=C(OC)C(OC)=C2)C3=C(C=C(OC)C(OC)=C3)CC1)=O)CC[[email protected]+]4(C)[[email protected]](CC5=CC=C(OC)C(OC)=C5)C6=C(C=C(OC)C(OC)=C6)CC4.O=S(C7=CC=CC=C7)([O-])=O.O=S(C8=CC=CC=C8)([O-])=O
InChI InChI=1S/C53H72N2O12.2C6H6O3S/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6;2*7-10(8,9)6-4-2-1-3-5-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3;2*1-5H,(H,7,8,9)/q+2;;/p-2/t42-,43-,54-,55-;;/m1../s1

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Safety Data of Cisatracurium (besylate)

Hazard Symbols:T Risk Statements:25-36 Safety Statements:45
Transport Information: HS Code: RTECS:
WGK Germany:

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:90-93°C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,249 mg/mL(200.24 mM);In vitro:Ethanol,249 mg/mL(200.24 mM);In vitro:Water,47 mg/mL(37.79 mM);
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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