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Zidovudine

(CAS: 30516-87-1)

Suppliers of Zidovudine

Company Name Email Tel Country
Aakash Chemicals and Dye-Stuffs, Inc. [email protected] 800 255 4855 USA

Fax: 630 469 2255Purity: Brand:

AbMole BioScience [email protected] 1-800-660-8580 USA

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Abcam [email protected] (888) 77-ABCAM (22226) USA

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Price and Availability: USD139/25mg ()

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Aladdin [email protected] 400 620 6333 China

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Price and Availability: RMB869/1g () RMB2239/5g ()

Alfa Chemistry [email protected] 1-201-478-8534 USA

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BOC Sciences [email protected] 1-631-504-6093

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Beijing JingSource Pharmaceutical Technology Co., Ltd. [email protected] +86 (10) 5286-5516 China

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BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD72/100mg () USD156/500mg ()

Carbosynth Limited [email protected] +44 (1635) 578-444

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Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Dimysh ( ShangHai ) Trading Co., Ltd. [email protected],[email protected] +86 (21) 5109-7611 China

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Ezhou Hengtong Weiye Chemical Co., Ltd. [email protected] +86 (711) 324-5607 China

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Jinan Dechenghemu Medical Technology Co., Ltd. [email protected] +86 (531) 8888-3739 China

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Lonzeal Pharmaceuticals Co., Ltd. [email protected] +86 (10) 8217-6280 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD72/100mg () USD156/500mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Price and Availability: USD55/5mg ()

Microbiologica Quimica e Farmaceutica Ltda. [email protected] +55 (21) 3296-3200 Brazil

Fax: +55 (21) 3296-3222Purity: Brand:

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD97/25mg (In stock) USD270/100mg (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR

Shanghai Desano Co., Ltd. [email protected] +86 (21) 5132-3300 China

Fax: +86 (21) 5132-3311Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD72/100mg () USD156/500mg ()

Sigma-Aldrich, Inc. [email protected] +86 (21) 6141-5566 / 800-819-3336 USA

Fax: Purity: Brand:

Price and Availability: USD321/400mg (usp)

Sinobond Imp. & Exp. (Ningbo) Co., Ltd. [email protected] +86 (574) 2766-9091 China

Fax: +86 (574) 2766-9090Purity: Brand:

Spectrum Chemical Mfg. Corp. [email protected] +1 (310) 516-8000 USA

Fax: +1 (310) 516-7512Purity: Brand:

Price and Availability: USD104/1g ()

Suchem Pharma Co., Ltd. [email protected],[email protected] +86 (577) 8117-2668 China

Fax: +86 (577) 5680-9275Purity: Brand:

Taizhou Ingore Bio & Tech Co., Ltd. [email protected] +86 (576) 8378-7222 China

Fax: +86 (576) 8613-7983Purity: Brand:

Taizhou Yojoy Chemical Co., Ltd. [email protected] +86 (576) 8783-1166 / +86 18605861109 China

Fax: +86 (576) 8783-1189Purity: Brand:

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD20/2mg () USD43/10mg () USD73/25mg () USD125/50mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

Tokyo Chemical Industry Co., Ltd. [email protected] 03-3668-0489 Japan

Fax: 03-3668-0520Purity: Brand:

Price and Availability: USD80/1g ()

UHN (Shanghai) Research & Development Co., Ltd. [email protected], [email protected] (86) 21-5895 8002 China

Fax: (86) 21-5895 8618Purity: > 98% Brand:

Price and Availability: USD480/1Kg (In stock)

VDM BIOCHEMICALS,Inc. [email protected] 1-440-786-9400 USA

Fax: 1-440-786-9410Purity: Brand:

Price and Availability: USD35/1g ()

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Background Information of Zidovudine

Zidovudine (Azidothymidine, AZT) is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. IC50 value: Target: NRTI; reverse-transcriptase AZT is a thymidine analogue.

Solubility of Zidovudine

Solubility Sources
H2O 50 mg/mL DMSO MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 53 mg/mL (198.32 mM); Water53 mg/mL warming (198.32 mM); Ethanol18 mg/mL warming (67.35 mM) Selleck Chemicals LLC
Soluble to 50 mM in water and to 100 mM in DMSO Tocris Bioscience Inc.

Storage Condition of Zidovudine

Storage Condition Sources
Store at -20°C Tocris Bioscience Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Anti-infection
Target HIV
Research Area Infection
Indications HIV-1 infection HIV infection Acquired immune deficiency syndrome

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Zidovudine Hospital Clinic of Barcelona HIV-1 infection 2001/11/30 Phase 4 Clinical
Zidovudine GlaxoSmithKline Inc HIV infection 2001/2/28 Phase 4 Clinical
Zidovudine Boehringer Ingelheim Corp Acquired immune deficiency syndrome 2003/6/30 2006/7/01 Phase 4 Clinical
Zidovudine Peking Union Medical College Hospital Acquired immune deficiency syndrome 2005/1/31 Phase 4 Clinical
Zidovudine Germans Trias i Pujol Hospital HIV-1 infection 2005/9/30 2007/6/30 Phase 4 Clinical
Zidovudine - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
267.24 C10H13N5O4 30516-87-1 Azidothymidine;AZT;ZDV; 1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

Structure Information of Zidovudine

Smiles O=C(C(C)=CN1[[email protected]@H](C2)O[[email protected]@H]([[email protected]]2N=[N+]=[N-])CO)NC1=O
InChI InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1

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Safety Data of Zidovudine

Hazard Symbols:Xn Risk Statements:40-36/37/38-20/21/22 Safety Statements:36/37/39-45-36-26
Transport Information: HS Code: RTECS:XP2072000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white solid Melting point:113-115 °C(lit.)
Boiling point: Flash Point:
Water Solubility: 1-5 g/100 mL at 17 ºC Solubility:In vitro:DMSO,53 mg/mL(198.32 mM);In vitro:Water,53 mg/mLwarmed(198.32 mM);In vitro:Ethanol,18 mg/mLwarmed(67.35 mM);
Density: Merck:10123
BRN: Refractive Index: 47 ° (C=1, H2O)
Vapour: EINECS:
Optical Rotation: alpha:

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