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Levoleucovorin (Calcium)

(CAS: 80433-71-2)

Suppliers of Levoleucovorin (Calcium)

Company Name Email Tel Country
AK Scientific, Inc. [email protected] 510-429-8835 USA

Fax: 510-429-8836 510-429-8836 510-429-8836Purity: Brand:

AbMole BioScience [email protected] 1-800-660-8580 USA

Fax: Purity: Brand:

Price and Availability: USD160/25mg (In Stock)

Abblis Chemicals LLC [email protected] Toll Free: 1-877-799-4928 (US and Canada only) Tel:+1-877-799-4928 USA

Fax: Fax:+1-713-664-0347Purity: Brand:

Price and Availability: USD110/10mg (In Stock)

Aladdin [email protected] 400 620 6333 China

Fax: 021 5102 6000Purity: Brand:

Price and Availability: RMB649/10mg () RMB6999/250 mg ()

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD60/100mg () USD72/500mg ()

Carbosynth Limited [email protected] +44 (1635) 578-444

Fax: +44 (1635) 579-444Purity: Brand:

Price and Availability: USD110/250mg ()

Lianyungang Jinkang Pharmaceutical Technology Co., Ltd. [email protected],[email protected] +86 (518) 8544-5517 China

Fax: +86 (518) 8544-5217Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/100mg () USD72/500mg ()
Quality Control & MSDS Files: LCMS HNMR MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD110/10mg (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC HNMR HPLC

Shandong Kingnod Pharmaceuticals Co., Ltd. [email protected] +86 (533) 815-5527 / +86 15053385713 China

Fax: Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD60/100mg () USD72/500mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD89/10mg () USD368/100mg ()

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Background Information of Levoleucovorin (Calcium)

Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid. IC50 value: Target: Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer.

Solubility of Levoleucovorin (Calcium)

Solubility Sources
DMSO MedChemexpress Co., Ltd.
(25°C) * In vitro Water 9 mg/mL (17.59 mM); DMSO<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of Levoleucovorin (Calcium)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage
Target Antifolate
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Levoleucovorin (Calcium) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
511.5 C20H21CaN7O7 80433-71-2 Calcium levofolinate;Elvorine;Isovorin;CL307782; calcium (S)-2-(4-((((S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioate

Structure Information of Levoleucovorin (Calcium)

Smiles O=C1C2=C(NC[[email protected]](CNC3=CC=C(C(N[[email protected]](C([O-])=O)CCC([O-])=O)=O)C=C3)N2C=O)NC(N)=N1.[Ca+2]
InChI InChI=1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12-,13-;/m0./s1

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Other Form Products of Levoleucovorin (Calcium)

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
Trimethoprim 738-70-5 C14H18N4O3 13
Calcium N5-methyltetrahydrofolate 26560-38-3 C20H23CaN7O6 8
Folinic acid 58-05-9 C20H23N7O7 8
Folinic acid (calcium salt pentahydrate) 6035-45-6 C20H21CaN7O7 7
Pemetrexed (disodium hemipenta hydrate) (1:2:2.5) 357166-30-4 C40H48N10Na4O17 13
Pemetrexed (disodium) 150399-23-8 C20H19N5Na2O6 21
Folinic acid (Calcium) 1492-18-8 C20H21CaN7O7 12
Pyrimethamine 58-14-0 C12H13ClN4 19
Levomefolate (calcium) 151533-22-1 C40H48CaN14O12 15
Levomefolic acid 31690-09-2 C20H25N7O6 13
Methotrexate 59-05-2 C20H22N8O5 31
Pemetrexed 137281-23-3 C20H21N5O6 8
Pralatrexate 146464-95-1 C23H23N7O5 7
QN254 C17H18ClN5O2 0
P218 C18H24N4O4 0
P65 C14H15Cl3N4O2 0
WR99210 47326-86-3 C14H18Cl3N5O2 0
Pemetrexed (disodium) 150399-23-8 C20H19N5Na2O6 3
Levomefolate (calcium) 151533-22-1 C20H23CaN7O6 5
Cycloguanil D6 C11H8D6ClN5 0

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Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:240-2500C (dec)
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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