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Guanfacine (hydrochloride)

(CAS: 29110-48-3)

Suppliers of Guanfacine (hydrochloride)

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AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD66/10mg () USD192/50mg ()

CacheSyn Inc. [email protected] +1 (416) 996-8186 Canada

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Carbosynth Limited [email protected] +44 (1635) 578-444

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Price and Availability: USD67/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Clearsynth Labs Limited [email protected] Worldwide Helpline No. +1-415-685-4395; US & Canada (Toll-free) : +1-800-650-8239; Europe : +44-20-3286-0885; India : +91-22-26355700 India

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Price and Availability: USD200/25mg ()

Combliss Healthcare Industrial Ltd. [email protected],[email protected] +86 18615688656 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD66/10mg () USD192/50mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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ProbeChem [email protected] 86-21-80183644

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Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

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Price and Availability: USD65/10mg ()

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD66/10mg () USD192/50mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .99 Brand: TargetMol

Price and Availability: USD99/5mg () USD136/10mg () USD176/50mg () USD308/100mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Price and Availability: USD75/10mg ()

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Background Information of Guanfacine (hydrochloride)

Guanfacine Hcl, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors.

Solubility of Guanfacine (hydrochloride)

Solubility Sources
DMSO 100 mM Water 100 mM MedChemexpress Co., Ltd.

Storage Condition of Guanfacine (hydrochloride)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Guanfacine (hydrochloride) Jpm Van Stralen Medicine Professional Corporation Attention deficit hyperactivity disorder 2013/10/31 2014/8/31 Phase 4 Clinical
Guanfacine (hydrochloride) Yale University Pervasive child developmental disorder 2011/12/31 2014/3/31 Phase 4 Clinical
Guanfacine (hydrochloride) Shire Pharmaceutical Development Ltd Attention deficit hyperactivity disorder 2009/11/30 2010/10/31 Phase 3 Clinical
Guanfacine (hydrochloride) Shire Pharmaceutical Development Ltd Attention deficit hyperactivity disorder 2006/9/30 2008/1/31 Phase 3 Clinical
Guanfacine (hydrochloride) Shire plc Attention deficit hyperactivity disorder 2012/3/31 2015/11/30 Phase 3 Clinical
Guanfacine (hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
282.55 C9H10Cl3N3O 29110-48-3 Guanfacine;Tenex;Intuniv; N-carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride

Structure Information of Guanfacine (hydrochloride)

Smiles O=C(NC(N)=N)CC1=C(Cl)C=CC=C1Cl.[H]Cl
InChI InChI=1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H

Related Products

Other Form Products of Guanfacine (hydrochloride)

Name CAS Formula Suppliers
Guanfacine 29110-47-2 C9H9Cl2N3O 10

Recommended Products in Same Target

Name CAS Formula Suppliers
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Nicergoline 27848-84-6 C24H26BrN3O3 13
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Tamsulosin 106133-20-4 C20H28N2O5S 11
UK 14,304 59803-98-4 C11H10BrN5 12
Guanfacine 29110-47-2 C9H9Cl2N3O 10
Propranolol (hydrochloride) 318-98-9 C16H22ClNO2 22
Guanabenz (Acetate) 23256-50-0 C10H12Cl2N4O2 14
Tetrahydrozoline (hydrochloride) 522-48-5 C13H17ClN2 18
Octopamine (hydrochloride) 770-05-8 C8H12ClNO2 24
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Norepinephrine (hydrochloride) 329-56-6 C8H12ClNO3 6
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(R)-(-)-Phenylephrine (hydrochloride) 61-76-7 C9H14ClNO2 21
Isoprenaline (hydrochloride) 51-30-9 C11H18ClNO3 19

Recommended Products in the Same Indication

Name CAS Formula Suppliers
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Bavisant (dihydrochloride hydrate) 1103522-80-0 C19H31Cl2N3O3 8
Naltrexone (Hydrochloride) 16676-29-2 C20H24ClNO4 16
GTS-21 (dihydrochloride) 156223-05-1 C19H22Cl2N2O2 10
Bavisant 929622-08-2 C19H27N3O2 7
Bavisant (dihydrochloride) 929622-09-3 C19H29Cl2N3O2 7

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,56 mg/mL(198.19 mM);In vitro:Ethanol,56 mg/mL(198.19 mM);In vitro:Water,30 mg/mL(106.17 mM);
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:249-443-3
Optical Rotation: alpha:

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