Phlorizin
(CAS: 60-81-1)
Background Information of Phlorizin
Phlorizin, a natural product and dietary constituent found in a number of fruit trees, is a 2'-glucoside of phloretin, Phlorizin is a competitive and classic inhibitor of hSGLT1(Ki=300 nM) and hSGLT2(Ki= 39 uM).
Storage Condition of Phlorizin
Quality Control and Spectral Data
Mechanism and Indications
Clinical Information
Product Name |
Sponsor & Collaborators |
Indications |
Start Date |
End Date |
Phase |
Phlorizin
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- |
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Not Found |
Phlorizin
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- |
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No Development Reported |
Chemical Information
M.Wt |
Formula |
CAS No. |
Synonyms |
436.41 |
C21H24O10 |
60-81-1 |
1-(2-(beta-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)-propan-1-on; 1-(2,4-dihydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one |
Structure Information of Phlorizin
Smiles |
O=C(CCC1=CC=C(O)C=C1)C(C(O)=CC(O)=C2)=C2O[[email protected]@H]3O[[email protected]](CO)[[email protected]@H](O)[[email protected]](O)[[email protected]]3O |
InChI |
InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1 |
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Name |
CAS |
Formula |
Suppliers |
Chemical and Physical Properties
Appearance:White to off-white Solid |
Melting point:113-114 °C(lit.) |
Boiling point: |
Flash Point: |
Water Solubility: |
Solubility: |
Density: |
Merck:7327 |
BRN: |
Refractive Index: -54 ° (C=3.2, 95% EtOH) |
Vapour: |
EINECS:200-487-1 |
Optical Rotation: |
alpha: |