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BGB-102

(CAS: 807640-87-5)

Suppliers of BGB-102

Company Name Email Tel Country
BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD1536/1mg () USD3072/5mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD1536/1mg () USD3072/5mg ()

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: >98% Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD1536/1mg () USD3072/5mg ()

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Background Information of BGB-102

BGB-102 is a potent multi-kinase inhibitor against EGFR, HER2, and HER4 with IC50s of 9.6 nM, 18 nM and 40.3 nM, respectively.

Solubility of BGB-102

Solubility Sources
Soluble in DMSO, not in water MedKoo Biosciences, Inc.

Storage Condition of BGB-102

Storage Condition Sources
Storage condition:Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Stock solution storage:0 - 4 C for short term (days to weeks), or -20 C for long term (months). Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. MedKoo Biosciences, Inc.

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
BGB-102 Johnson & Johnson Pharmaceutical Research & Development, L.L.C.|Janssen Pharmaceutica N.V., Belgium Protein Kinase Inhibitors|Antineoplastic Protocols|Clinical Trial, Phase 1|Maximum Tolerated Dose|Pharmacokinetics|Advanced Malignancies|Solid Malignancies 2006/8/01 Phase 1

Chemical Information

M.Wt Formula CAS No. Synonyms
457.36 C22H25BrN4O2 807640-87-5 JNJ-26483327;BGB102;BGB 102;JNJ26483327;JNJ 26483327;

Structure Information of BGB-102

Smiles CN1CCCCCOC(C(OC)=C2)=CC3=C2N=CN/C3=NC4=CC(Br)=CC=C4C1
InChI InChI=1S/C22H25BrN4O2/c1-27-8-4-3-5-9-29-21-11-17-19(12-20(21)28-2)24-14-25-22(17)26-18-10-16(23)7-6-15(18)13-27/h6-7,10-12,14H,3-5,8-9,13H2,1-2H3,(H,24,25,26)

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Chemical and Physical Properties

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Reference

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