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Erlotinib (mesylate)

(CAS: 248594-19-6)

Suppliers of Erlotinib (mesylate)

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD51/100mg () USD153/500mg ()

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD60/100mg () USD90/500mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/100mg () USD90/500mg ()

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD60/100mg () USD90/500mg ()

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Background Information of Erlotinib (mesylate)

Erlotinib mesylate (R 1415; CP-358774; OSI-774)is a directly acting inhibitor of human EGFR tyrosine kinase with an IC50 of 2 nM. IC50 Value: 2 nM [1] in vitro: CP-358,774 inhibits the proliferation of DiFi human colon tumor cells at submicromolar concentrations in cell culture and blocks cell cycle progression at the G1 phase.

Solubility of Erlotinib (mesylate)

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Erlotinib (mesylate)

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MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Erlotinib (mesylate) Eisai Inc Metastatic non small cell lung cancer 2010/2/28 2013/12/31 Phase 2 Clinical
Erlotinib (mesylate) Eisai Inc Metastatic non small cell lung cancer 2004/12/31 2008/6/01 Phase 2 Clinical
Erlotinib (mesylate) Genentech Inc Glioblastoma 2003/7/31 2005/10/31 Phase 2 Clinical
Erlotinib (mesylate) Sarah Cannon Research Institute Renal cell carcinoma 2004/6/30 2011/8/31 Phase 2 Clinical
Erlotinib (mesylate) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
489.54 C23H27N3O7S 248594-19-6 Tarceva;CP-358774;OSI-774;NSC 718781;R 1415; N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine methanesulfonate

Structure Information of Erlotinib (mesylate)

Smiles CS(=O)(O)=O.COCCOC1=CC2=NC=NC(NC3=CC=CC(C#C)=C3)=C2C=C1OCCOC
InChI InChI=1S/C22H23N3O4.CH4O3S/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;1-5(2,3)4/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H3,(H,2,3,4)

Related Products

Other Form Products of Erlotinib (mesylate)

Name CAS Formula Suppliers
Erlotinib impurity B 183321-83-7 C21H20ClN3O3 4
Erlotinib impurity A 183321-85-9 C21H20ClN3O3 3
Erlotinib 183321-74-6 C22H16D8ClN3O4 16
Erlotinib (Hydrochloride) 183319-69-9 C22H24ClN3O4 22
Erlotinib (D6 hydrochloride) 1189953-78-3 C22H18D6ClN3O4 2

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LY2603618 911222-45-2 C18H22BrN5O3 8
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Temozolomide 85622-93-1 C6H6N6O2 27

Chemical and Physical Properties

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