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Gefitinib (hydrochloride)

(CAS: 184475-55-6)

Suppliers of Gefitinib (hydrochloride)

Company Name Email Tel Country
Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD60/100mg () USD72/500mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/100mg () USD72/500mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Price and Availability: USD300/1g ()

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD60/100mg () USD72/500mg ()

Shanghai Taiheng Industry Co., Ltd. [email protected] +86 (21) 6469-9426 China

Fax: +86 (21) 6469-9429Purity: Brand:

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Background Information of Gefitinib (hydrochloride)

Gefitinib Hcl(ZD-1839 Hcl) is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.

Solubility of Gefitinib (hydrochloride)

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Gefitinib (hydrochloride)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Gefitinib (hydrochloride) Guangdong Association of Clinical Trials Metastatic non small cell lung cancer 2011/6/30 2014/4/30 Phase 3 Clinical
Gefitinib (hydrochloride) National Cancer Institute of Canada Bladder cancer 2006/4/30 2012/1/01 Phase 3 Clinical
Gefitinib (hydrochloride) National Cancer Center of Korea Metastatic lung cancer 2005/10/31 2010/3/31 Phase 3 Clinical
Gefitinib (hydrochloride) National Cancer Institute of Naples Metastatic non small cell lung cancer 2006/12/31 2012/6/30 Phase 3 Clinical
Gefitinib (hydrochloride) Sarah Cannon Research Institute Carcinoma 2003/9/30 2009/6/30 Phase 3 Clinical
Gefitinib (hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
483.36 C22H25Cl2FN4O3 184475-55-6 4-(3-Chloro-4-fluorophenylamino)-7-methoxy-6-[3-(4-morpholinyl)propoxy]quinazoline hydrochloride; N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine hydrochloride

Structure Information of Gefitinib (hydrochloride)

Smiles COC1=CC2=C(C=C1OCCCN3CCOCC3)C(NC4=CC(Cl)=C(F)C=C4)=NC=N2.Cl
InChI InChI=1S/C22H24ClFN4O3.ClH/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15;/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27);1H

Related Products

Other Form Products of Gefitinib (hydrochloride)

Name CAS Formula Suppliers
Gefitinib 184475-35-2 C22H24ClFN4O3 20
Gefitinib (Dihydrochloride) 184475-56-7 C22H26Cl3FN4O3 2
Gefitinib (D8) 857091-32-8 C22H16D8ClFN4O3 1

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Recommended Products in the Same Indication

Name CAS Formula Suppliers
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Sunitinib 557795-19-4 C22H27FN4O2 18
N-Hydroxy-3-(3-phenylsulfamoylphenyl)acrylamide 414864-00-9 C15H14N2O4S 4
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AXL1717 477-47-4 C22H22O8 18

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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