• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

1-NM-PP1

(CAS: 221244-14-0)

Suppliers of 1-NM-PP1

Company Name Email Tel Country
AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Price and Availability: USD64/5mg ()

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD90/5mg (In Stock)

Axon Medchem BV [email protected];[email protected] +31 50 3118007 Netherlands

Fax: +31 50 3600390Purity: Brand:

Price and Availability: USD114/5mg (In Stock)

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD114/5mg () USD180/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Price and Availability: USD86/1mg ()

Chendu Sinostandards Bio-Tech Co., Ltd [email protected] 0086-28-83243029 China

Fax: 0086-28-8324 0018Purity: Brand:

Price and Availability: RMB3510/5mg ()

Clearsynth Labs Limited [email protected] Worldwide Helpline No. +1-415-685-4395; US & Canada (Toll-free) : +1-800-650-8239; Europe : +44-20-3286-0885; India : +91-22-26355700 India

Fax: Purity: Brand:

Price and Availability: USD5500/25mg ()

EMD Millipore USA

Fax: Purity: Brand:

Price and Availability: USD104/1mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD114/5mg () USD180/10mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: >98% Brand:

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Price and Availability: USD94/1mg ()

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD114/5mg () USD180/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD71/2mg () USD125/5mg () USD212/10mg () USD569/50mg ()

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of 1-NM-PP1

1NM-PP1(PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors(IC50=28 uM vSrc; 4.2 nM v-Src-as1 I338G). IC50 Value: 4.2 nM (v-Src-as1 I338G) [1] Target: Src Family Kinase PP1 Analog II, 1NM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.

Solubility of 1-NM-PP1

Solubility Sources
DMSO MedChemexpress Co., Ltd.
Soluble in DMSO, not in water MedKoo Biosciences, Inc.

Storage Condition of 1-NM-PP1

Storage Condition Sources
Storage condition:Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Stock solution storage:0 - 4 C for short term (days to weeks), or -20 C for long term (months). Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. MedKoo Biosciences, Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage
Target CDK
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
1-NM-PP1 - Not Found
1-NM-PP1 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
331.41 C20H21N5 221244-14-0 PP1 Analog II;1-NM-PP 1; 1-(tert-butyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Structure Information of 1-NM-PP1

Smiles CC(N1N=C(CC2=CC=CC3=C2C=CC=C3)C4=C(N)N=CN=C41)(C)C
InChI InChI=1S/C20H21N5/c1-20(2,3)25-19-17(18(21)22-12-23-19)16(24-25)11-14-9-6-8-13-7-4-5-10-15(13)14/h4-10,12H,11H2,1-3H3,(H2,21,22,23)

Related Products

Other Form Products of 1-NM-PP1

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
LY2857785 1619903-54-6 C26H36N6O 7
THZ2 1604810-84-5 C31H28ClN7O2 5
Palbociclib (isethionate) 827022-33-3 C26H35N7O6S 18
CDK9-IN-6 1391855-95-0 C27H37ClN6O2 4
ML167 1285702-20-6 C19H17N3O3 7
AMG 925 1401033-86-0 C26H29N7O2 12
LDC000067 1073485-20-7 C18H18N4O3S 9
LEE011 (succinate hydrate) 1374639-79-8 C27H38N8O6X 7
LEE011 (succinate) 1374639-75-4 C27H36N8O5 7
LEE011 (hydrochloride) 1211443-80-9 C23H31ClN8O 6
LEE011 1211441-98-3 C23H30N8O 17
WHI-P180 (hydrochloride) 153437-55-9 C16H16ClN3O3 5
Wogonin 632-85-9 C16H12O5 21
WHI-P180 211555-08-7 C16H15N3O3 8
THZ1 1604810-83-4 C31H28ClN7O2 9
Senexin A 1366002-50-7 C17H14N4 5
CDK4-IN-1 1256963-02-6 C22H29ClN8 8
Palbociclib (hydrochloride) 827022-32-2 C24H30ClN7O2 16
Purvalanol B 212844-54-7 C20H25ClN6O3 12
NU6102 444722-95-6 C18H22N6O3S 1

Recommended Products in the Same Indication

Name CAS Formula Suppliers

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy 1-NM-PP1 | 1-NM-PP1 IC50 | 1-NM-PP1 price | 1-NM-PP1 cost | 1-NM-PP1 solubility | 1-NM-PP1 purchase | 1-NM-PP1 manufacturer | 1-NM-PP1 research buy | 1-NM-PP1 order | 1-NM-PP1 MSDS | 1-NM-PP1 chemical structure | 1-NM-PP1 Storage condition | 1-NM-PP1 molecular weight | 1-NM-PP1 mw | 1-NM-PP1 datasheet | 1-NM-PP1 supplier | 1-NM-PP1 cell line | 1-NM-PP1 NMR | 1-NM-PP1 MS | 1-NM-PP1 IR | 1-NM-PP1 solubility | 1-NM-PP1 Safe information | 1-NM-PP1 Qc and Spectral Information | 1-NM-PP1 Clinical Information | 1-NM-PP1 Clinical Trial | 1-NM-PP1 Route of Synthesis | 1-NM-PP1 storage condition | 1-NM-PP1 diseases and conditions | 1-NM-PP1 flash point | 1-NM-PP1 boiling point | 1-NM-PP1 melting point | 1-NM-PP1 storage condition | 1-NM-PP1 brand