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A 419259 (trihydrochloride)

(CAS: 1435934-25-0)

Suppliers of A 419259 (trihydrochloride)

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD185/10mg (Ship Within 10-14 Days) USD551/50mg (Ship Within 10-14 Days)

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Price and Availability: USD35/1mg ()

Key Organics Ltd. [email protected] +44 (1840) 212-137 UK

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: >98% Brand:

Price and Availability: USD180/10mg (In stock) USD630/50mg (In stock)
Quality Control & MSDS Files: HNMR NP-HPLC MSDS

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: >98% Brand:

Price and Availability: USD195/10mg (In stock) USD580/50mg (In stock)

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

Price and Availability: USD265/10mg ()

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Background Information of A 419259 (trihydrochloride)

A 419259 3Hcl is an apoptosis inducing agent that inhibits Src family kinases (c-Src).

Solubility of A 419259 (trihydrochloride)

Solubility Sources
Soluble to 100 mM in water and to 100 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of A 419259 (trihydrochloride)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [NP-HPLC] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Protein Tyrosine Kinase/RTK
Target Src
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
A 419259 (trihydrochloride) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
592.0 C29H37Cl3N6O 1435934-25-0 A419259 trihydrochloride;A-419259 trihydrochloride;RK 20449 trihydrochloride;RK20449 trihydrochloride;RK-20449 trihydrochloride; 7-((1r,4r)-4-(4-methylpiperazin-1-yl)cyclohexyl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride

Structure Information of A 419259 (trihydrochloride)

Smiles NC1=C2C(N([[email protected]]3CC[[email protected]](N4CCN(C)CC4)CC3)C=C2C5=CC=C(OC6=CC=CC=C6)C=C5)=NC=N1.[H]Cl.[H]Cl.[H]Cl
InChI InChI=1S/C29H34N6O.3ClH/c1-33-15-17-34(18-16-33)22-9-11-23(12-10-22)35-19-26(27-28(30)31-20-32-29(27)35)21-7-13-25(14-8-21)36-24-5-3-2-4-6-24;;;/h2-8,13-14,19-20,22-23H,9-12,15-18H2,1H3,(H2,30,31,32);3*1H/t22-,23-;;;

Related Products

Other Form Products of A 419259 (trihydrochloride)

Name CAS Formula Suppliers
A 419259 364042-47-7 C29H34N6O 4

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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