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Bergapten

(CAS: 484-20-8)

Suppliers of Bergapten

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand:

Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 0.96 Brand: Alfa Chemistry

Andard-Mount Company Limited [email protected] +44 (0) 20 8991 5150 UNITED KINGDOM

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Baoji Herbest Bio-Tech Co., Ltd. [email protected]; [email protected]; [email protected] +86 (917) 888-8998 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD144/1g () USD576/5g ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD144/1g () USD576/5g ()

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD144/1g () USD576/5g ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD89/10mg () USD146/25mg () USD209/50mg ()

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Background Information of Bergapten

5-Methoxypsoralen, a naturally occurring linear furocoumarin, has been successfully used in combination with ultraviolet (UV) A irradiation [psoralen plus UV (PUVA)] to manage psoriasis and vitiligo; inhibit proliferation in the human hepatocellular carcinoma cell line. IC50 value: Target: anti cancer in vitro: 5-MOP increased the activity of NATand also increased the further metabolism of AAF at 24 h in the rat stomach.

Solubility of Bergapten

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Bergapten

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease Autophagy
Target Autophagy Cytochrome P450
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Bergapten - Phase 3 Clinical
Bergapten - Phase 3

Chemical Information

M.Wt Formula CAS No. Synonyms
216.19 C12H8O4 484-20-8 5-Methoxypsoralen; 4-Methoxy-7H-furo[3,2-g]chromen-7-one; 4-methoxy-7H-furo[3,2-g]chromen-7-one

Structure Information of Bergapten

Smiles COC1=C(C=CC2=O)C(O2)=CC3=C1C=CO3
InChI InChI=1S/C12H8O4/c1-14-12-7-2-3-11(13)16-10(7)6-9-8(12)4-5-15-9/h2-6H,1H3

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:190-193 °C(lit.)
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,5 mg/mL(23.12 mM);In vitro:Water,Insoluble;In vitro:Ethanol,Insoluble;
Density: Merck:1157
BRN: Refractive Index:
Vapour: EINECS:207-604-5
Optical Rotation: alpha:

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