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Cucurbitacin E

(CAS: 18444-66-1)

Suppliers of Cucurbitacin E

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Adipogen Corporation [email protected] (858) 457-8383 USA

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD144/5mg () USD228/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Extrasynthese Chemical S.A.S. [email protected] +33 (47) 898-2034 France

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD144/5mg () USD228/10mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

Shanghai Forever Biotech Co., Ltd. [email protected] +86 (21) 6973-4790 China

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD144/5mg () USD228/10mg ()

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Background Information of Cucurbitacin E

Cucurbitacin E is a natural compound which from the climbing stem of Cucumic melo L. Cucurbitacin E significantly suppresses the activity of the cyclin B1/CDC2 complex.

Solubility of Cucurbitacin E

Solubility Sources
10 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of Cucurbitacin E

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways NF-κB Autophagy
Target Autophagy NF-κB
Research Area Cancer

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Cucurbitacin E - Not Found
Cucurbitacin E - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
556.69 C32H44O8 18444-66-1 [(E,6R)-6-[(8S,9R,10R,13R,14S,16R,17R)-2,16-Dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate; (R,E)-6-((8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-4,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl acetate

Structure Information of Cucurbitacin E

Smiles C[[email protected]@]([[email protected]@]1([H])[[email protected]]2(C)[[email protected]@](C=C3O)([H])C(C(C)(C)C3=O)=CC1)(C[[email protected]]4O)[[email protected]@](CC2=O)(C)[[email protected]@]4([H])[[email protected]@](C)(O)C(/C=C/C(C)(C)OC(C)=O)=O
InChI InChI=1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3/b13-12+/t19-,21-,22+,25+,29+,30-,31+,32+/m1/s1

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Chemical and Physical Properties

Appearance: Melting point:228-234°C
Boiling point: Flash Point:
Water Solubility: Solubility:Soluble in DMSO.
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:242-325-2
Optical Rotation: alpha:

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