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Cortisone

(CAS: 53-06-5)

Suppliers of Cortisone

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Aladdin [email protected] 400 620 6333 China

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Price and Availability: RMB486/1g () RMB1246/5g ()

Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 98% Brand: Alfa Chemistry

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BOC Sciences [email protected] 1-631-504-6093

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Beijing Hengye Zhongyuan Chemical Co., Ltd. [email protected] +86 (10) 8580-1612 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Carbosynth Limited [email protected] +44 (1635) 578-444

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Clearsynth Labs Limited [email protected] Worldwide Helpline No. +1-415-685-4395; US & Canada (Toll-free) : +1-800-650-8239; Europe : +44-20-3286-0885; India : +91-22-26355700 India

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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ProbeChem [email protected] 86-21-80183644

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Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .97 Brand: TargetMol

Price and Availability: USD24/5mg () USD43/10mg () USD74/20mg () USD168/100mg () USD298/250mg ()

Tianjin Heowns Biochemical Technology Co., Ltd. [email protected] (022) 83717335, 83717309, 8371735 China

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Tokyo Chemical Industry Co., Ltd. [email protected] 03-3668-0489 Japan

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Toronto Research Chemicals Inc. [email protected] +1 (416) 665-9696 Canada

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Xiangyang Jinsheng Pharmaceutical Co., Ltd. [email protected] +86 (710) 357-7774 China

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Background Information of Cortisone

Cortisone is a naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE.

Solubility of Cortisone

Solubility Sources
10 mM in DMSO CHEMSCENE, LLC
10 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of Cortisone

Storage Condition Sources
4°C MedChemexpress Co., Ltd.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways GPCR/G Protein
Target Glucocorticoid Receptor
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Cortisone - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
360.44 C21H28O5 53-06-5 17,21-Dihydroxypregn-4-ene-3,11,20-trione; (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,10,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11(2H,6H)-dione

Structure Information of Cortisone

Smiles C[[email protected]]1(CC2=O)[[email protected]](CC[[email protected]]1(O)C(CO)=O)([H])[[email protected]@](CC3)([H])[[email protected]@]2([H])[[email protected]](CC4)(C)C3=CC4=O
InChI InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

Related Products

Other Form Products of Cortisone

Name CAS Formula Suppliers
Cortisone (acetate) 50-04-4 C23H30O6 26

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Meprednisone 1247-42-3 C22H28O5 16
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Dexamethasone (acetate) 1177-87-3 C24H31FO6 18
Fluticasone (propionate) 80474-14-2 C25H31F3O5S 20
Betamethasone (hydrochloride) 956901-32-9 C22H30ClFO5 6
Hydrocortisone 50-23-7 C21H30O5 25
Prednisolone 50-24-8 C21H28O5 25
Cortisone (acetate) 50-04-4 C23H30O6 26
AL 082D06 256925-03-8 C23H24ClN3O2 11
Mometasone furoate 83919-23-7 C32H32Cl2O8 18
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Safety Data of Cortisone

Hazard Symbols:F,T,Xn Risk Statements:11-23/24/25-39/23/24/25-63 Safety Statements:22-24/25-45-36/37-16-7
Transport Information: HS Code: RTECS:GM9020000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:223-228 °C (dec.)(lit.)
Boiling point: Flash Point:
Water Solubility: Solubility:Soluble in DMSO
Density:1.28±0.1 g/cm3 (20 ºC 760 Torr), Calc.* Merck:2539
BRN: Refractive Index: 210 ° (C=1, EtOH)
Vapour: EINECS:200-162-4
Optical Rotation: alpha:

Reference

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