• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

AMG 837

(CAS: 865231-46-5)

Suppliers of AMG 837

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

Fax: Purity: Brand:

Price and Availability: USD180/10mg (In stock)

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

Price and Availability: USD2471/1g ()

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD156/5mg () USD228/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Matrix Scientific [email protected] Orders: 800-733-0244 (US & CAN),All other calls: 803-788-9494 USA

Fax: Orders: 800-580-6330 (US & CAN), All other faxes: 803-788-9419Purity: Brand:

Price and Availability: USD742/250mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD156/5mg () USD228/10mg ()

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD156/5mg () USD228/10mg ()

Shanghai XingMo Biotechnology Co., Ltd. [email protected] 13524779951 CHINA

Fax: Purity: > 98% Brand: X-MoBio

Price and Availability: USD1400/1g (In stock)

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of AMG 837

AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. IC50 value: 13 nM (EC50) [1] Target: GPR40 agonist AMG 837 displayed the expected two-fold increase in potency on GPR4 (EC50 = 13 [±7] nM) compared to the racemic compound and its activity crossed over to the rat and mouse forms of GPR40 (EC50 = 23 and 13 nM, respectively).

Solubility of AMG 837

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of AMG 837

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways GPCR/G Protein
Target GPR40
Research Area Metabolic Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
AMG 837 - Not Found
AMG 837 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
438.44 C26H21F3O3 865231-46-5 AMG-837;AMG837; (S)-3-(4-((4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid

Structure Information of AMG 837

Smiles OC(C[[email protected]](C#CC)C1=CC=C(C=C1)OCC2=CC=CC(C3=CC=C(C(F)(F)F)C=C3)=C2)=O
InChI InChI=1S/C26H21F3O3/c1-2-4-21(16-25(30)31)20-9-13-24(14-10-20)32-17-18-5-3-6-22(15-18)19-7-11-23(12-8-19)26(27,28)29/h3,5-15,21H,16-17H2,1H3,(H,30,31)/t21-/m0/s1

Related Products

Other Form Products of AMG 837

Name CAS Formula Suppliers
AMG 837 (calcium hydrate) 1259389-38-2 C26H22F3O4- 9
AMG 837 (sodium salt) 865231-45-4 C26H20F3NaO3 6

Recommended Products in Same Target

Name CAS Formula Suppliers
AMG 837 (calcium hydrate) 1259389-38-2 C26H22F3O4- 9
AMG 837 (sodium salt) 865231-45-4 C26H20F3NaO3 6
GPR40 Activator 1 1309435-60-6 C31H31NO3S 6
TUG-770 1402601-82-4 C19H14FNO2 13
GW9508 885101-89-3 C22H21NO3 22
TAK-875 1000413-72-8 C29H32O7S 16
GW-1100 306974-70-9 C27H25FN4O4S 9
GPR40 Activator 2 1312787-30-6 C28H29NO6S2 6
DC260126 346692-04-4 C32H31N5O 7
M-I C19H22O5S 0
T-1676427 1000414-39-0 C29H32O8S 0
JTT-851 C23H28O3 0
Astellas C27H30N4O4 0
MK-2305 905723-46-8 C19H13ClF3NO4S 0
Mochida 1469495-84-8 C30H35NO6S 0
BMS-986118 1610562-74-7 C25H28ClF3N4O4 2
AM-6226 C32H36F2O4 0
GPR40 agonist 1 1312788-44-5 C24H20O3 0
GPR40 agonist 2 C25H22O3 0
GPR40 agonist 3 C23H18O3 0

Recommended Products in the Same Indication

Name CAS Formula Suppliers

Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy AMG 837 | AMG 837 IC50 | AMG 837 price | AMG 837 cost | AMG 837 solubility | AMG 837 purchase | AMG 837 manufacturer | AMG 837 research buy | AMG 837 order | AMG 837 MSDS | AMG 837 chemical structure | AMG 837 Storage condition | AMG 837 molecular weight | AMG 837 mw | AMG 837 datasheet | AMG 837 supplier | AMG 837 cell line | AMG 837 NMR | AMG 837 MS | AMG 837 IR | AMG 837 solubility | AMG 837 Safe information | AMG 837 Qc and Spectral Information | AMG 837 Clinical Information | AMG 837 Clinical Trial | AMG 837 Route of Synthesis | AMG 837 storage condition | AMG 837 diseases and conditions | AMG 837 flash point | AMG 837 boiling point | AMG 837 melting point | AMG 837 storage condition | AMG 837 brand