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(±)-Bisoprolol (hemifumarate)

(CAS: 104344-23-2)

Suppliers of (±)-Bisoprolol (hemifumarate)

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AA Blocks LLC [email protected] +1 858-523-8231

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AbMole BioScience [email protected] 1-800-660-8580 USA

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BLD Pharmatech [email protected] +86-21-61629022

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BOC Sciences [email protected] 1-631-504-6093

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Beijing Eagle Sky Pharmatech Co., Ltd. [email protected],[email protected] +86 (10) 5979-9429 China

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Beijing Gaobo Pharm-Chemicals Tech. Co., Ltd [email protected] 010-52266256 CHINA

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Beijing Mesochem Technology Co., Ltd. [email protected],[email protected] +86 (10) 6540-5760 / 6737-4028 / +86 13366977697 China

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD82/100mg () USD119/200mg ()

Hanzhong Hanjiang-Venturepharm Pharmaceutical Ltd. [email protected] +86 (916) 223-2535 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD82/100mg () USD119/200mg ()
Quality Control & MSDS Files: LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD100/25mg (In stock) USD220/10mM/1mLIn DMSO (In stock) USD350/100mg (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD82/100mg () USD119/200mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .99 Brand: TargetMol

Price and Availability: USD24/2mg () USD98/10mg () USD156/25mg () USD198/100mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Background Information of (±)-Bisoprolol (hemifumarate)

Bisoprolol is a selective type β1 adrenergic receptor blocker. Target: Adrenergic Receptor Approved: July 31, 1992 Bisoprolol, on beta 1-adrenoceptor peptide induced autoimmune myocardial damage.

Solubility of (±)-Bisoprolol (hemifumarate)

Solubility Sources
DMSO 88 mg/mL Water 88 mg/mL Ethanol 88 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 88 mg/mL (199.31 mM); Water88 mg/mL (199.31 mM); Ethanol88 mg/mL (199.31 mM) Selleck Chemicals LLC
Soluble to 50 mM in water Tocris Bioscience Inc.

Storage Condition of (±)-Bisoprolol (hemifumarate)

Storage Condition Sources
Store at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways GPCR/G Protein
Target Adrenergic Receptor
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
(±)-Bisoprolol (hemifumarate) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
766.96 C40H66N2O12 104344-23-2 Bisoprolol hemifumarate salt; 1-(4-((2-isopropoxyethoxy)methyl)phenoxy)-3-(isopropylamino)propan-2-ol hemifumarate

Structure Information of (±)-Bisoprolol (hemifumarate)

Smiles OC(CNC(C)C)COC1=CC=C(COCCOC(C)C)C=C1.OC(CNC(C)C)COC2=CC=C(COCCOC(C)C)C=C2.OC(/C=C/C(O)=O)=O
InChI InChI=1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

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Safety Data of (±)-Bisoprolol (hemifumarate)

Hazard Symbols:Xn,Xi Risk Statements:22 Safety Statements:
Transport Information: HS Code: RTECS:UB8390000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:100°C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,88 mg/mL(199.31 mM);In vitro:Water,88 mg/mL(199.31 mM);In vitro:Ethanol,88 mg/mL(199.31 mM);
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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