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(CAS: 142128-59-4)

Suppliers of (+)-Ketoconazole

Company Name Email Tel Country
CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: >98% Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: >98% Brand:

Price and Availability: USD99/1g (Get quote) USD338/5g (Get quote)

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: >98% Brand:

Price and Availability: USD120/500mg (Get quote) USD200/1g (Get quote)

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Background Information of (+)-Ketoconazole

(+)-Ketoconazole is an imidazole anti-fungal agent, a CYP3A4 inhibitor. Target: CYP3A4 (+)-Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligospermia, and decreased testosterone levels, in men being treated for chronic mycotic infections [1].

Solubility of (+)-Ketoconazole

Solubility Sources
DMSO 3 mg/mL; Water <1 mg/mL MedChemexpress Co., Ltd.

Storage Condition of (+)-Ketoconazole

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease Anti-infection
Target Fungal Cytochrome P450
Research Area Infection

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
(+)-Ketoconazole - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
531.43 C26H28Cl2N4O4 142128-59-4 1-(4-(4-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethanone

Structure Information of (+)-Ketoconazole

Smiles ClC(C=C1)=CC(Cl)=C1[[email protected]@]2(CN3C=CN=C3)OC[[email protected]](COC4=CC=C(N5CCN(C(C)=O)CC5)C=C4)O2
InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m0/s1

Related Products

Other Form Products of (+)-Ketoconazole

Name CAS Formula Suppliers
Ketoconazole 65277-42-1 C26H28Cl2N4O4 12

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Chemical and Physical Properties

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