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Scopolamine (hydrobromide)

(CAS: 114-49-8)

Suppliers of Scopolamine (hydrobromide)

Company Name Email Tel Country
Alkaloids Corporation [email protected] +91 (33) 2475-2952 India

Fax: Purity: Brand:

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD60/100mg () USD144/500mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Chemada Fine Chemicals Ltd. [email protected] +972 (8) 998-3421 / 998-3422 Israel

Fax: +972 (8) 998-3598Purity: Brand:

Jai Radhe Sales [email protected] +91 (79) 2643-1096 India

Fax: +91 (79) 2656-9884Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/100mg () USD144/500mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD60/100mg () USD144/500mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD35/5mg () USD88/20mg () USD148/50mg () USD230/100mg () USD382/200mg ()

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Background Information of Scopolamine (hydrobromide)

Scopolamine hydrobromide is a competitive muscarinic acetylcholine receptor (mAChR) with an IC50 of 55.3 ± 4.3 nM. Target: mAChR Scopolamine (USAN), also known as levo-duboisine and hyoscine, sold as Scopoderm, is a tropane alkaloid drug with muscarinic antagonist effects.

Solubility of Scopolamine (hydrobromide)

Solubility Sources
DMSO 77 mg/mL (200 mM); Water 77 mg/mL (200 mM) MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 76 mg/mL (197.78 mM); Water76 mg/mL (197.78 mM); Ethanol<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of Scopolamine (hydrobromide)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Neuronal Signaling GPCR/G Protein
Target mAChR 5-HT Receptor
Research Area Neurological Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Scopolamine (hydrobromide) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
384.26 C17H22BrNO4 114-49-8 Hyoscine hydrobromide; (S)-(1R,2R,4S,5S,7s)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 3-hydroxy-2-phenylpropanoate hydrobromide

Structure Information of Scopolamine (hydrobromide)

Smiles CN1[[email protected]@]2([H])[[email protected]](O3)([H])[[email protected]]3([H])[[email protected]]1([H])C[[email protected]](OC([[email protected]](CO)C4=CC=CC=C4)=O)C2.Br
InChI InChI=1S/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1

Related Products

Other Form Products of Scopolamine (hydrobromide)

Name CAS Formula Suppliers
Scopolamine (butylbromide) 149-64-4 C21H30BrNO4 16
Scopolamine 51-34-3 C17H21NO4 9

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Safety Data of Scopolamine (hydrobromide)

Hazard Symbols:Xn Risk Statements:22 Safety Statements:36
Transport Information: HS Code: RTECS:YM4550000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:195-199 °C (dry matter)(lit.)
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,76 mg/mL(197.78 mM);In vitro:Water,76 mg/mL(197.78 mM);In vitro:Ethanol,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:204-050-6
Optical Rotation: alpha:

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